The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Hagel et al..
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy, Nature Chemical Biology, 2010
??ber die Kondensation von Opians??ure und Phtalaldehyds??ure mit Cyclohexanon und Di??thylketon, Monatshefte f??r Chemie und verwandte Teile anderer Wissenschaften