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3Anticancer Antibiotics, New Approaches to Natural Anticancer Drugs Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells, Cancer Chemotherapy and Pharmacology A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors, Investigational New Drugs