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ChemSpider 2D Image | (+)-Clopidogrel bisulfate | C16H18ClNO6S2

(+)-Clopidogrel bisulfate

  • Molecular FormulaC16H18ClNO6S2
  • Average mass419.900 Da
  • Monoisotopic mass419.026398 Da
  • ChemSpider ID103200
  • defined stereocentres - 1 of 1 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(+)-Clopidogrel bisulfate
(+)-Clopidogrel hydrogen sulfate
(2S)-(2-Chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)acétate de méthyle sulfate (1:1) [French] [ACD/IUPAC Name]
(2S)-(2-chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)éthanoate de méthyle sulfate
(S)-(+)-Clopidogrel bisulfate
(S)-(+)-Clopidogrel Hydrogensulfate
(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
(S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate
(S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate
120202-66-6 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

08I79HTP27 [DBID]
D00769 [DBID]
DV-7314 [DBID]
UNII:08I79HTP27 [DBID]
UNII-08I79HTP27 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      IRRITANT Matrix Scientific 047886
    • Target Organs:

      P2 Receptor antagonist TargetMol T0182L
    • Drug Status:

      approved BIONET-Key Organics KS-1045
    • Compound Source:

      synthetic Microsource [01503710]
    • Bio Activity:

      7-TM Receptors Tocris Bioscience 1820
      GPCR/G protein MedChem Express HY-17459
      GPCR/G protein; MedChem Express HY-17459
      Neuroscience TargetMol T0182L
      P2Y Receptor MedChem Express HY-17459
      P2Y Receptor TargetMol T0182L
      Purinergic P2Y Receptors Tocris Bioscience 1820
      S-(+)-Clopidogrel Hydrogen Sulfate is the S enantiomer of clopidogrel and a P2Y12 receptor inhibitor. MedChem Express http://www.medchemexpress.com/rocuronium-bromide.html, HY-17459
      S-(+)-Clopidogrel Hydrogen Sulfate is the S enantiomer of clopidogrel and a P2Y12 receptor inhibitor. ;Target: P2Y ReceptorClopidogrel is an effective antiplatelet agent useful for the treatment of ischemic cerebrovascular, cardiac, and peripheral arterial disease. Clopidogrel abolishes the inhibitory P2Y(AC) receptor-mediated ADP effects on prostaglandin E(1)-stimulated, cAMP-dependent phosphorylation of VASP without affecting epinephrine, thrombin, and thromboxane signaling. VASP phosphorylation is known to be closely correlated with the inhibition of platelet and fibrinogen receptor (glycoprotein IIb/IIIa) activation. Therefore, inhibition of the platelet P2Y(AC) ADP receptor and its intracellular signaling, including decreased VASP phosphorylation, is suggested as a molecular mechanism of clopidogrel action [1]. Clopidogrel ingestion reduced the thrombus volume significantly (p < 0.05) at 100 and 2600 s-1 (39 and 51% respectively). clopidogrel reduced significantly the fibrinop MedChem Express HY-17459
      Selective P2Y12 antagonist Tocris Bioscience 1820
      Selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (?)-clopidogrel hydrochloride (Cat. No. 2490). Tocris Bioscience 1820
      Selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (+/-)-clopidogrel hydrochloride (Cat. No. 2490). Tocris Bioscience 1820
      Selective, high affinity P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity. Active enantiomer of (±)-clopidogrel hydrochloride (Cat. No. 2490). Tocris Bioscience 1820

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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