ChemSpider 2D Image | glycopyrronium bromide | C19H28BrNO3

glycopyrronium bromide

  • Molecular FormulaC19H28BrNO3
  • Average mass398.335 Da
  • Monoisotopic mass397.125244 Da
  • ChemSpider ID11201

  • Charge - Charge

More details:

Featured data source
The Merck Index Online

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-methyl-3-pyrrolidyl α-cyclopentylmandelate methobromide
1-methyl-3-pyrrolidyl α-phenyl-α-cyclopentylglycolate methobromide
209-887-0 [EINECS]
3-(2-Phenyl-2-cyclopentylglycoloyloxy)-1,1-dimethylpyrrolidinium Bromide
3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidin-1-ium bromide
3-[2-Cyclopentyl(hydroxy)phenylacetoxy]-1,1-dimethylpyrrolidinium bromide [ACD/IUPAC Name]
3-[2-Cyclopentyl(hydroxy)phenylacetoxy]-1,1-dimethylpyrrolidiniumbromid [German] [ACD/IUPAC Name]
3-{[cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidinium bromide
3-{[Cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidiniumbromid [German]
3-Hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AHR-504 [DBID]
NSC 250836 [DBID]
NSC 251251 [DBID]
NSC 251252 [DBID]
68EL47CXSP [DBID]
AHR 504 [DBID]
D00540 [DBID]
RSJ51H051V [DBID]
VGB6MN0Z00 [DBID]
W76196A5NR [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      AChR antagonist TargetMol T2387

    • Chemical Class:

      A quaternary ammonium salt composed of 3-{[cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium and bromide ions in a 1:1 ratio. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:90972, CHEBI:90972

    • Bio Activity:

      Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.; IC50 Value:; Target: mAChR (Muscarinic acetylcholine receptor M1); in vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. MedChem Express HY-17465
      Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.;IC50 Value:;Target: mAChR (Muscarinic acetylcholine receptor M1);In vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. Kinetics studies, however, showed that glycopyrrolate dissociates slowly from HASM muscarinic receptors (60% protection against [3H]-NMS binding at 30 nM) compared to ipratropium bromide [1].;In vivo: Glycopyrrolate (1 mg) tablets were then administered, starting with one tablet daily the third week and increasing the daily dose by one tablet per week until a maximum of four tablets during week six and 4 days of week seven when the daily dose was reduced to two tablets for 3 days. glycopyrrolate can be given in controlled doses provided that an adequate medical assessment has been undertaken [2]. Glycopyrrolate has a slow and erratic absorption from the gastrointestinal system, but even low plasma levels are associated with a distinct MedChem Express HY-17465
      GPCR/G protein MedChem Express HY-17465
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-17465
      mAChR MedChem Express HY-17465
      mAChR M1 TargetMol T2387
      Neuroscience TargetMol T2387

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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