ChemSpider 2D Image | 2H9NV66W0I | C20H27ClN2O4

2H9NV66W0I

  • Molecular FormulaC20H27ClN2O4
  • Average mass394.892 Da
  • Monoisotopic mass394.165924 Da
  • ChemSpider ID114897

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

122892-31-3 [RN]
2H9NV66W0I
Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy-, hydrochloride (1:1) [ACD/Index Name]
Itopride (hydrochloride)
Itopride HCl
Itopride hydrochloride
MFCD00881710 [MDL number]
N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4-dimethoxybenzamide hydrochloride
N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramide Hydrochloride
N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

122892-31-3 122898-67-3 [DBID]
D02729 [DBID]
HSR 803 [DBID]
HSR-803 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      AChR antagonist;Dopamine Receptor antagonist TargetMol T1552

    • Bio Activity:

      AChE MedChem Express HY-B0732
      Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor. MedChem Express
      Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor.; Target: AChE; Itopride is a gastroprokinetic benzamide derivative. MedChem Express HY-B0732
      Itopride hydrochloride is an AChE inhibitor (acetylcholinesterase) and D2DR inhibitor.;Target: AChE;Itopride is a gastroprokinetic benzamide derivative. The IC50 of itopride with AChE (2.04 +/- 0.27 microM) was, however, 100-fold less than that with BuChE, whereas in the case of neostigmine with AChE (11.3 +/- 3.4 nM), it was 10-fold less. The inhibitory effect of itopride on cholinesterase (ChE) activity in guinea pig gastrointestine was much weaker than that on pure AChE. the IC50s of itopride against ChE activities were found to be about 0.5 microM. The IC50 of itopride for electric eel and guinea pig gastrointestinal AChE inhibition was 200 times and 50 times as large as that of neostigmine, respectively [1]. MedChem Express HY-B0732
      Musciarinic AChR;Dopamine receptor TargetMol T1552
      Neuronal Signaling MedChem Express HY-B0732
      Neuronal Signaling; MedChem Express HY-B0732
      Neuroscience TargetMol T1552

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


Advertisement