ChemSpider 2D Image | (+)-(S)-Citalopram oxalate | C22H23FN2O5

(+)-(S)-Citalopram oxalate

  • Molecular FormulaC22H23FN2O5
  • Average mass414.427 Da
  • Monoisotopic mass414.159088 Da
  • ChemSpider ID129278

  • defined stereocentres - 1 of 1 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(+)-(S)-Citalopram oxalate
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate (1:1) [ACD/IUPAC Name]
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile oxalate
(1S)-1-[3-(diméthylamino)propyl]-1-(4-fluorophényl)-1,3-dihydro-2-benzofurane-5-carbonitrile oxalate
(1S)-1-[3-(Diméthylamino)propyl]-1-(4-fluorophényl)-1,3-dihydro-2-benzofurane-5-carbonitrile oxalate (1:1) [French] [ACD/IUPAC Name]
1,4-Benzenediamine, ethanedioate (1:1) [ACD/Index Name]
219861-08-2 [RN]
5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-, ethanedioate (1:1) [ACD/Index Name]
Escitalopram [BAN] [INN] [JAN] [USAN] [Wiki]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D02567 [DBID]
MLD-55 [DBID]
UNII-DJ1F4R673N [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      5-HT Transporters Tocris Bioscience 4796
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio [HB1804]
      Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. MedChem Express
      Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM.;Target: SSRIsEscitalopram, the S-enantiomer of citalopram, belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Escitalopram may be used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). Escitalopram has no significant affinity for adrenergic (alpha1, alpha2, beta), cholinergic, GABA, dopaminergic, histaminergic, serotonergic (5HT1A, 5HT1B, 5HT2), or benzodiazepine receptors; antagonism of such receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs. The chronic administration of escitalopram is found to downregulate brain norepinephrine receptors, as has been observed with other drugs effective in the treatment of major depressive disorder. Escitalopram does not inhibit monoamine oxidase. MedChem Express HY-14258A
      Neuronal Signaling; MedChem Express HY-14258A
      Neurotransmitter Transporters Tocris Bioscience 4796
      Receptors & Transporters/Transporters/5-HT uptake & transport Hello Bio [HB1804]
      Selective 5-HT reuptake inhibitor (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a S-enantiomer and eutomer of citalopram (Cat. No. 1427). Tocris Bioscience 4796
      Selective serotonin reuptake inhibitor (SSRI) Tocris Bioscience 4796
      Selective serotonin reuptake inhibitor (SSRI) Hello Bio [HB1804]
      Selective serotonin reuptake inhibitor (SSRI) (K<sub>i</sub> values are 0.89, 8150, and 10500 nM for SET, NET and DAT transporters respectively). Hello Bio [HB1804]
      Selective serotonin reuptake inhibitor (SSRI) (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a S-enantiomer and eutomer of citalopram (Cat. No. 1427). Tocris Bioscience 4796
      SSRIs MedChem Express HY-14258A
      Transporters Tocris Bioscience 4796

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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