ChemSpider 2D Image | sodium valproate | C8H15NaO2

sodium valproate

  • Molecular FormulaC8H15NaO2
  • Average mass166.193 Da
  • Monoisotopic mass166.096970 Da
  • ChemSpider ID13428

  • Charge - Charge

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

sodium valproate [JP15]
1069-66-5 [RN]
213-961-8 [EINECS]
2-Propylpentanoate de sodium [French] [ACD/IUPAC Name]
2-Propylpentanoic acid sodium
2-Propylvaleric acid sodium salt
5VOM6GYJ0D
DEPACON [Trade name]
Depakene [Trade name]
Depakin [Trade name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4212221 [DBID]
A-44090 [DBID]
CHEBI:9925 [DBID]
D00710 [DBID]
EU-0100889 [DBID]
Lopac-P-4543 [DBID]
NCGC00016192-01 [DBID]
P4543_SIGMA [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      GABAR;HDAC inhibitor TargetMol T1602

    • Chemical Class:

      The sodium salt of valproic acid. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9925, CHEBI:9925

    • Bio Activity:

      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio [HB0867]
      Cell process/Stem cells/Dedifferentiation Hello Bio [HB0867]
      Chromatin/Epigenetic;Neuroscience TargetMol T1602
      Deacetylases Tocris Bioscience 2815
      Enzymes Tocris Bioscience 2815
      Enzymes/Deacetylase/Histone deacetylase (HDAC) Hello Bio [HB0867]
      GABAR;HDAC2, HDAC9 TargetMol T1602
      Histone deacetylase inhibitor Tocris Bioscience 2815
      Histone deacetylase inhibitor (IC<sub>50</sub> = 400 &micro;M at HDAC1). Shows multitude of biological actions. Can be used to produce pluripotent stem cells (iPS cells) with only Oct4 and Sox2 factors required in addition. Activates Wnt-dependent gene expression and shows anti-inflammatory, anti-cancer anti-epileptic and neuroprotective actions. Blood-brain barrier permeable . Hello Bio [HB0867]
      Histone deacetylase inhibitor (IC50 = 400 ?M) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases A? production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem c ells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Tocris Bioscience 2815
      Histone deacetylase inhibitor (IC50 = 400 ?M) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases A? production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Tocris Bioscience 2815
      Histone deacetylase inhibitor (IC50 = 400 muM) that exhibits anticancer, anti-inflammatory and neuroprotective effects. Displays anticonvulsive activity via an increase in GABA levels and decreases Abeta production in animal models of Alzheimer's disease. Also attenuates NMDA-mediated excitation, blocks voltage-gated Na+ channels and modulates firing of neurons. Enables induction of pluripotent stem cells from somatic cells by Oct4 and Sox2. Can induce autophagy by inhibiting inositol synthesis. Tocris Bioscience 2815
      Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells. Hello Bio [HB0867]
      Histone Deacetylases Tocris Bioscience 2815

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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