ChemSpider 2D Image | Atazanavir sulfate | C38H54N6O11S

Atazanavir sulfate

  • Molecular FormulaC38H54N6O11S
  • Average mass802.934 Da
  • Monoisotopic mass802.357117 Da
  • ChemSpider ID139472
  • defined stereocentres - 4 of 4 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[(1S,4S,5S,10S)-4-benzyl-1,10-bis(1,1-diméthyléthyl)-5-hydroxy-2,9,12-trioxo-7-(4-pyridin-2-ylbenzyl)-13-oxa-3,7,8,11-tétraazatétradéc-1-yl]carbamate de méthyle sulfate (salt)
{(5S,10S,11S,14S)-11-Benzyl-10-hydroxy-15,15-diméthyl-5-(2-méthyl-2-propanyl)-3,6,13-trioxo-8-[4-(2-pyridinyl)benzyl]-2-oxa-4,7,8,12-tétraazahexadécan-14-yl}carbamate de méthyle sulfate (1:1) (non-pre ferred name) [French] [ACD/IUPAC Name]
229975-97-7 [RN]
4MT4VIE29P
Atazanavir sulfate [JAN] [USAN]
BMS-232632-05
BMS-232632-05 {Sulfate}
butanoic acid, 2-[(methoxycarbonyl)amino]-3,3-dimethyl-, 2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-[(methoxycarbonyl)amino]-3,3-dimethyl-1-oxobutyl]amino]-4-phenylbutyl]-2-[[4-(2-pyridinyl)phenyl]methyl]hydrazi
Butanoic acid, 2-[(methoxycarbonyl)amino]-3,3-dimethyl-, 2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-[(methoxycarbonyl)amino]-3,3-dimethyl-1-oxobutyl]amino]-4-phenylbutyl]-2-[[4-(2-pyridinyl)phenyl]methyl]hydrazi de, (2S)-, sulfate (1:1) (salt) [ACD/Index Name]
butanoic acid, 2-[(methoxycarbonyl)amino]-3,3-dimethyl-, 2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-[(methoxycarbonyl)amino]-3,3-dimethyl-1-oxobutyl]amino]-4-phenylbutyl]-2-[[4-(2-pyridinyl)phenyl]methyl]hydrazide, (2S)-, sulfate (1:1) (salt)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BMS-232632 [DBID]
CGP-73547 [DBID]
D01276 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Target Organs:

      HIV Protease inhibitor TargetMol T0100
    • Bio Activity:

      Anti-infection MedChem Express HY-17367A
      Anti-infection; Metabolism/Protease; MedChem Express HY-17367A
      Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. MedChem Express
      Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.; Target: HIV-1 protease inhibitor; Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. MedChem Express HY-17367A
      Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.;Target: HIV-1 protease inhibitorAtazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor. It has a pharmacokinetic profile that supports once-daily dosing and has demonstrated a unique resistance profile and superior virologic potency compared with other antiretrovirals in vitro. In subjects with HIV, atazanavir (400 mg once daily) produced rapid and sustained improvements in viral load and CD4 counts in both antiretroviral-naive as well as previously treated patients when used in combination with dual nucleoside reverse transcriptase inhibitor (NRTI) treatment [1].After intravenous (iv), oral (po) and intraportal (ip) administration of ATV at a dosage of 7 mg/kg, AUCs in HL rats were 12.41, 5.24 and 8.89 microg/mLh, respectively, and were significantly higher than those in control rats (4.09, 1.70 and 3.38 microg/mLh). Despit MedChem Express HY-17367A
      HIV MedChem Express HY-17367A
      HIV HIV Protease MedChem Express HY-17367A
      HIV Protease TargetMol T0100
      Proteases/Proteasome; Microbiology & Virology TargetMol T0100

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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