ChemSpider 2D Image | Melittin | C131H229N39O31

Melittin

  • Molecular FormulaC131H229N39O31
  • Average mass2846.463 Da
  • Monoisotopic mass2844.754150 Da
  • ChemSpider ID17290230

  • defined stereocentres - 28 of 28 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

20449-79-0 [RN]
Glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-argin yl-L-lysyl-L-arginyl-L-glutaminyl-L-glutamamide [ACD/IUPAC Name]
Glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-thréonyl-L-thréonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-séryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-argin yl-L-lysyl-L-arginyl-L-glutaminyl-L-glutamamide [French] [ACD/IUPAC Name]
Glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-argin yl-L-lysyl-L-arginyl-L-glutaminyl-L-glytamamid [German] [ACD/IUPAC Name]
Glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutamamide
L-Glutamamide, glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl- L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl- [ACD/Index Name]
L-Glutamamide, glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-
Melittin [Wiki]
Melittin from honey bee venom
MFCD00076868 [MDL number]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

20449-79-0,123168-46-7 [DBID]
M2272_SIGMA [DBID]
M4171_SIGMA [DBID]
UN1231 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH<smallsub>2</smallsub> res idues joined in sequence. It is the principal active component of bee venom. ChEBI CHEBI:6736
      A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 res; idues joined in seq uence. It is the principal active component of bee venom. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6736
      A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in seque nce. It is the principal active component of bee venom. ChEBI CHEBI:6736

    • Bio Activity:

      Cell Biology Tocris Bioscience 1193
      G Protein (Heterotrimeric) Tocris Bioscience 1193
      Inhibits Gs and stimulates Gi activity Tocris Bioscience 1193
      Inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor. Tocris Bioscience 1193
      Signal Transduction Tocris Bioscience 1193

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.635
Molar Refractivity: 728.5±0.5 cm3
#H bond acceptors: 70
#H bond donors: 50
#Freely Rotating Bonds: 104
#Rule of 5 Violations: 3
ACD/LogP: -1.32
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area: 1152 Å2
Polarizability: 288.8±0.5 10-24cm3
Surface Tension: 57.6±7.0 dyne/cm
Molar Volume: 2034.1±7.0 cm3

Click to predict properties on the Chemicalize site


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