ChemSpider 2D Image | diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa2O1,O1]platinum | C6H12N2O4Pt

diammine[cyclobutane-1,1-dicarboxylato(2-)-κ2O1,O1]platinum

  • Molecular FormulaC6H12N2O4Pt
  • Average mass371.254 Da
  • Monoisotopic mass371.044495 Da
  • ChemSpider ID21865132

  • Charge - Charge

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

Diammin[1,1-cyclobutandicarboxylato(2-)-κ2O1,O1]platin [German] [ACD/IUPAC Name]
Diammine[1,1-cyclobutanedicarboxylato(2-)-κ2O1,O1]platine [French] [ACD/IUPAC Name]
Diammine[1,1-cyclobutanedicarboxylato(2-)-κ2O1,O1]platinum [ACD/IUPAC Name]
diammine[cyclobutane-1,1-dicarboxylato(2-)-κ2O1,O1]platinum
Platinum, diammine[1,1-cyclobutanedicarboxylato(2-)-κO1,κO1]- [ACD/Index Name]
platinum, diammine[1,1-cyclobutanedicarboxylato(2-)-κO1,κO1]-
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-κ(2)O,O']platinum
[41575-94-4] [RN]
41575-94-4 [RN]
Carboplatin [USAN] [Wiki]
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and disp lays lower nephrotoxicity than analog cisplatin (Cat. No. 2251). Tocris Bioscience 2626
      Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (Cat. No. 2251). Tocris Bioscience 2626
      Apoptosis Tocris Bioscience 2626
      Apoptosis Inducers Tocris Bioscience 2626
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB3824
      Cell Biology Tocris Bioscience 2626
      Cell process/DNA / RNA & protein synthesis Hello Bio HB3824
      Cisplatin analog. Blocks DNA replication and transcription. Hello Bio HB3824
      DNA cross-linking antitumor agent Tocris Bioscience 2626
      Potent platinum-based antineoplastic agent. Analog of cisplatin with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage. Hello Bio HB3824

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors: 6
#H bond donors: 4
#Freely Rotating Bonds: 2
#Rule of 5 Violations:
ACD/LogP:
ACD/LogD (pH 5.5):
ACD/BCF (pH 5.5):
ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
ACD/KOC (pH 7.4):
Polar Surface Area: 53 Å2
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site


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