ChemSpider 2D Image | PS48 | C17H15ClO2

PS48

  • Molecular FormulaC17H15ClO2
  • Average mass286.753 Da
  • Monoisotopic mass286.076050 Da
  • ChemSpider ID24604576

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acid [ACD/IUPAC Name]
(2z)-5-(4-Chlorophenyl)-3-Phenylpent-2-Enoic Acid
(2Z)-5-(4-Chlorphenyl)-3-phenyl-2-pentensäure [German] [ACD/IUPAC Name]
1180676-32-7 [RN]
2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)- [ACD/Index Name]
5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid
Acide (2Z)-5-(4-chlorophényl)-3-phényl-2-penténoïque [French] [ACD/IUPAC Name]
MFCD17215962 [MDL number]
PS 48
PS48
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      PDK-1 MedChem Express HY-15967
      PDK1 activator Tocris Bioscience 4087
      Phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 ?M). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. Tocris Bioscience 4087
      PI3K/Akt/mTOR MedChem Express HY-15967
      PI3K/Akt/mTOR; MedChem Express HY-15967
      PS48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator with Kd value of 10.3 ?M; binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. MedChem Express HY-15967

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 444.1±24.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.1 mmHg at 25°C
Enthalpy of Vaporization: 74.0±3.0 kJ/mol
Flash Point: 222.4±22.9 °C
Index of Refraction: 1.609
Molar Refractivity: 81.0±0.3 cm3
#H bond acceptors: 2
#H bond donors: 1
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 1
ACD/LogP: 5.59
ACD/LogD (pH 5.5): 3.82
ACD/BCF (pH 5.5): 271.97
ACD/KOC (pH 5.5): 1000.53
ACD/LogD (pH 7.4): 2.02
ACD/BCF (pH 7.4): 4.28
ACD/KOC (pH 7.4): 15.73
Polar Surface Area: 37 Å2
Polarizability: 32.1±0.5 10-24cm3
Surface Tension: 49.2±3.0 dyne/cm
Molar Volume: 234.1±3.0 cm3

Click to predict properties on the Chemicalize site


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