ChemSpider 2D Image | NVP-BGT226 | C32H29F3N6O6

NVP-BGT226

  • Molecular FormulaC32H29F3N6O6
  • Average mass650.604 Da
  • Monoisotopic mass650.210083 Da
  • ChemSpider ID28189082

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2Z)-2-Butendisäure --8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluormethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]chinolin-2-on (1:1) [German] [ACD/IUPAC Name]
1245537-68-1 [RN]
2H-Imidazo[4,5-c]quinolin-2-one, 1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-, (2Z)-2-butenedioate (1:1) [ACD/Index Name]
8-(6-Methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one (2Z)-2-butenedioate (1:1) [ACD/IUPAC Name]
Acide (2Z)-2-butènedioïque - 8-(6-méthoxy-3-pyridinyl)-3-méthyl-1-[4-(1-pipérazinyl)-3-(trifluorométhyl)phényl]-1,3-dihydro-2H-imidazo[4,5-c]quinoléin-2-one (1:1) [French] [ACD/IUPAC Name]
BGT226 (NVP-BGT226)
BGT-226 MALEATE
NVP-BGT226
(2Z)-BUT-2-ENEDIOIC ACID; 8-(6-METHOXYPYRIDIN-3-YL)-3-METHYL-1-[4-(PIPERAZIN-1-YL)-3-(TRIFLUOROMETHYL)PHENYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE
(Z)-but-2-enedioic acid and 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4YG62LG876 [DBID]
UNII:4YG62LG876 [DBID]
UNII-4YG62LG876 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      The maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2<element>H</element>-imidazo[4,5-<ital>c</ital>]quinolin-2-one. A dual PI3K/mTOR in hibitor. ChEBI CHEBI:71953
      The maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. ChEBI CHEBI:71953

    • Bio Activity:

      NVP-BGT226(BGT 226) is a novel class I PI3K/mTOR inhibitor for PI3K?/?/? with IC50 of 4 nM/63 nM/38 nM.; IC50 value: 4 nM/63 nM/38 nM(PI3K?/?/?) [1]; Target: PI3K; in vitro: The anti-proliferative and pro-apoptotic effects of NVP-BGT226 are independent of bcr-abl status. MedChem Express HY-13334
      PI3K MedChem Express HY-13334
      PI3K/Akt/mTOR MedChem Express HY-13334
      PI3K/Akt/mTOR ; MedChem Express HY-13334

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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