ChemSpider 2D Image | BMS-754807 | C23H24FN9O

BMS-754807

  • Molecular FormulaC23H24FN9O
  • Average mass461.495 Da
  • Monoisotopic mass461.208771 Da
  • ChemSpider ID30922819

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluor-3-pyridinyl)-2-methylprolinamid [German] [ACD/IUPAC Name]
1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoro-3-pyridinyl)-2-methylprolinamide [ACD/IUPAC Name]
1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoro-3-pyridinyl)-2-méthylprolinamide [French] [ACD/IUPAC Name]
2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl- [ACD/Index Name]
BMS-754807
(2S)-1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide
(S)-1-(4-((5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO)PYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)-N-(6-FLUOROPYRIDIN-3-YL)-2-METHYLPYRROLIDINE-2-CARBOXAMIDE.
1-{4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]PYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL}-N-(6-FLUOROPYRIDIN-3-YL)-2-METHYLPYRROLIDINE-2-CARBOXAMIDE
1001350-96-4 [RN]
MFCD18633202

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

W9E3353E8J [DBID]
  • Miscellaneous

    • Target Organs:

      IGF-1R inhibitor; c-MET inhibitor; Aurora Kinase inhibitor; FLT3 inhibitor; JAK inhibitor TargetMol T2349

    • Bio Activity:

      IGF-1R; Insulin Receptor;TrkB;Met;TrkA;Aurora A;Aurora B;RON;FLT3;JAK2 TargetMol T2349
      Tyrosine Kinase/Adaptors; JAK/STAT Signaling TargetMol T2349

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.6±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.795
Molar Refractivity: 123.6±0.5 cm3
#H bond acceptors: 10
#H bond donors: 3
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 1.76
ACD/LogD (pH 5.5): 1.64
ACD/BCF (pH 5.5): 10.13
ACD/KOC (pH 5.5): 175.64
ACD/LogD (pH 7.4): 1.70
ACD/BCF (pH 7.4): 11.55
ACD/KOC (pH 7.4): 200.30
Polar Surface Area: 116 Å2
Polarizability: 49.0±0.5 10-24cm3
Surface Tension: 67.7±7.0 dyne/cm
Molar Volume: 290.6±7.0 cm3

Click to predict properties on the Chemicalize site


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