ChemSpider 2D Image | Vericiguat | C19H16F2N8O2

Vericiguat

  • Molecular FormulaC19H16F2N8O2
  • Average mass426.379 Da
  • Monoisotopic mass426.136414 Da
  • ChemSpider ID32700337

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

{4,6-Diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate de méthyle [French] [ACD/IUPAC Name]
1350653-20-1 [RN]
Carbamic acid, N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-, methyl ester [ACD/Index Name]
LV66ADM269
Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamate [ACD/IUPAC Name]
methyl N-(4,6-diamino-2-{5-fluoro-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)carbamate
Methyl-{4,6-diamino-2-[5-fluor-1-(2-fluorbenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}carbamat [German] [ACD/IUPAC Name]
vericiguat [Spanish] [INN]
Vericiguat [INN]
vériciguat [French] [INN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

9805 [DBID]
  • Miscellaneous

    • Chemical Class:

      A pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substitu ted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure. ChEBI CHEBI:142432

    • Therapeutical Effect:

      To mitigate the risk of cardiovascular death and hospitalization for?chronic heart failure FDA Verquvo

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.6±0.1 g/cm3
Boiling Point: 535.9±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.4 mmHg at 25°C
Enthalpy of Vaporization: 81.2±3.0 kJ/mol
Flash Point: 277.9±30.1 °C
Index of Refraction: 1.736
Molar Refractivity: 104.8±0.5 cm3
#H bond acceptors: 10
#H bond donors: 5
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 2
ACD/LogP: 0.20
ACD/LogD (pH 5.5): 1.82
ACD/BCF (pH 5.5): 14.11
ACD/KOC (pH 5.5): 231.49
ACD/LogD (pH 7.4): 1.82
ACD/BCF (pH 7.4): 14.11
ACD/KOC (pH 7.4): 231.50
Polar Surface Area: 147 Å2
Polarizability: 41.5±0.5 10-24cm3
Surface Tension: 62.7±7.0 dyne/cm
Molar Volume: 260.8±7.0 cm3

Click to predict properties on the Chemicalize site


Advertisement