ChemSpider 2D Image | Propafenone hydrochloride | C21H28ClNO3

Propafenone hydrochloride

  • Molecular FormulaC21H28ClNO3
  • Average mass377.905 Da
  • Monoisotopic mass377.175781 Da
  • ChemSpider ID33715

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-Propafenone Hydrochloride
(RS)-Propafenone Hydrochloride
1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride
1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone Hydrochloride
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenyl-1-propanone hydrochloride (1:1) [ACD/IUPAC Name]
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phényl}-3-phényl-1-propanone, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenyl-1-propanonhydrochlorid (1:1) [German] [ACD/IUPAC Name]
1-{2-[2-hydroxy-3-(propylamino)propoxy]phényl}-3-phénylpropan-1-one chlorhydrate
1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride
1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride (1:1)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

33XCH0HOCD [DBID]
CHEBI:8466 [DBID]
UNII:33XCH0HOCD [DBID]
D00640 [DBID]
EU-0100919 [DBID]
MLS000069682 [DBID]
P4670_SIGMA [DBID]
Prestwick_831 [DBID]
SMR000058493 [DBID]
WZ 884 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Potassium Channel inhibitor;Sodium Channel inhibitor TargetMol T0866

    • Chemical Class:

      A hydrochloride that is the monohydrochloride salt of propafenone. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used in the management of supraventricular and ventricular arrhythmias. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8466, CHEBI:8466

    • Bio Activity:

      Membrane Tranporter/Ion Channel MedChem Express HY-B0432A
      Membrane Tranporter/Ion Channel; MedChem Express HY-B0432A
      Membrane Transporter/Ion Channel TargetMol T0866
      MRP1;Potassium Channel ;Sodium channel TargetMol T0866
      Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias. MedChem Express
      Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.; Target: Sodium Channel; Propafenone Hydrochloride is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. MedChem Express HY-B0432A
      Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.;Target: Sodium ChannelPropafenone Hydrochloride is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a bet MedChem Express HY-B0432A
      Sodium Channel MedChem Express HY-B0432A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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