ChemSpider 2D Image | N~5~-(6-Aminohexyl)-N~7~-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride | C22H34Cl2N6

N5-(6-Aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride

  • Molecular FormulaC22H34Cl2N6
  • Average mass453.452 Da
  • Monoisotopic mass452.222198 Da
  • ChemSpider ID35517723

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

N5-(6-Aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidin-5,7-diamindihydrochlorid [German] [ACD/IUPAC Name]
N5-(6-Aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride [ACD/IUPAC Name]
N5-(6-Aminohexyl)-N7-benzyl-3-isopropylpyrazolo[1,5-a]pyrimidine-5,7-diamine, dichlorhydrate [French] [ACD/IUPAC Name]
Pyrazolo[1,5-a]pyrimidine-5,7-diamine, N5-(6-aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)-, hydrochloride (1:2) [ACD/Index Name]
1883548-83-1 [RN]
BS 181 dihydrochloride
BS-181 (dihydrochloride)
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Cyclin-dependent Kinase Tocris Bioscience 5608
      Enzymes Tocris Bioscience 5608
      Kinases Tocris Bioscience 5608
      Selective cdk7 inhibitor Tocris Bioscience 5608
      Selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice. Tocris Bioscience 5608
      Selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice. Tocris Bioscience 5608

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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