ChemSpider 2D Image | Vecuronium bromide | C34H57BrN2O4

Vecuronium bromide

  • Molecular FormulaC34H57BrN2O4
  • Average mass637.731 Da
  • Monoisotopic mass636.350159 Da
  • ChemSpider ID36357

  • Charge - Charge

    defined stereocentres - 10 of 10 defined stereocentres

More details:

Featured data source
The Merck Index Online

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane bromide
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-16-(1-methyl-1-piperidiniumyl)-2-(1-piperidinyl)androstanbromid [German] [ACD/IUPAC Name]
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-16-(1-methyl-1-piperidiniumyl)-2-(1-piperidinyl)androstane bromide [ACD/IUPAC Name]
(2β,3α,5α,16β,17β)-3,17-Diacetoxy-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane bromide
1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide
256-723-9 [EINECS]
50700-72-6 [RN]
7E4PHP5N1D
Androstane-3,17-diol, 16-(1-methyl-1-piperidiniumyl)-2-(1-piperidinyl)-, bromide, diacetate (ester), (2β,3α,5α,16β,17β)- (1:1) [ACD/Index Name]
Bromure de (2β,3α,5α,16β,17β)-3,17-diacétoxy-16-(1-méthyl-1-pipéridiniumyl)-2-(1-pipéridinyl)androstane [French] [ACD/IUPAC Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4837308 [DBID]
5100 [DBID]
7164568 [DBID]
D00767 [DBID]
NC-45 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      AChR antagonist TargetMol T1594

    • Chemical Class:

      The organic bromide salt of a 5<stereo>alpha</stereo>-androstane compound having 3<stereo>alpha</stereo>-acetoxy-, 17<stereo>beta</stereo>-acetoxy-, 2<stereo>beta</stereo>-piperidinino- and 16<stereo> beta</stereo>-<element>N</element>-methylpiperidinium substituents. ChEBI CHEBI:9940
      The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16; beta-N-methylpiperidinium substituents. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:9940
      The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium substituents. ChEBI CHEBI:9940

    • Bio Activity:

      Membrane Tranporter/Ion Channel MedChem Express HY-B0118A
      Membrane Tranporter/Ion Channel; Neuronal Signaling; MedChem Express HY-B0118A
      nAChR MedChem Express HY-B0118A
      Neuronal AChR TargetMol T1594
      Neuroscience TargetMol T1594
      Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents. MedChem Express
      Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents.; Target: nAChR; Vecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking a gents. MedChem Express HY-B0118A
      Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents.;Target: nAChRVecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. In adolescents the vecuronium requirement was less than in children and was comparable to that reported in adults in other studies (89 +/- 13 micrograms.kg-1.hr-1) [1]. Infusions of Vecuronium provided much smoother control of neuromuscular blockade than did pancuronium. No cardiovascular side-effects were noted even at the greatest dose (0.12 mg kg-1) used. Vecuronium has clear advantages over pancuronium and represents a potentially valuable addition to the armamentarium of clinically useful muscle relaxants [2]. The onset times of the 0.6 and 0.9 mg x kg(-1) of Org 9426 groups were 84.6 and MedChem Express HY-B0118A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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