ChemSpider 2D Image | Meropenem | C17H31N3O8S

Meropenem

  • Molecular FormulaC17H31N3O8S
  • Average mass437.508 Da
  • Monoisotopic mass437.183197 Da
  • ChemSpider ID389923
  • defined stereocentres - 6 of 6 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
(4R,5S,6S)-3-{[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäuretrihydrat [German] [ACD/IUPAC Name]
(4R,5S,6S)-3-{[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate [ACD/IUPAC Name]
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)-, hydrate (1:3) [ACD/Index Name]
Acide (4R,5S,6S)-3-{[(3S,5S)-5-(diméthylcarbamoyl)-3-pyrrolidinyl]sulfanyl}-6-[(1R)-1-hydroxyéthyl]-4-méthyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ène-2-carboxylique, trihydrate [French] [ACD/IUPAC Name]
FV9J3JU8B1
Meropenem (hydrate)
meropenem trihydrate [JP15]
MFCD08600005 [MDL number]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D02222 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Antibacterial MedChem Express HY-13678A
      Anti-infection MedChem Express HY-13678A
      Anti-infection; MedChem Express HY-13678A
      Meropenem (trihydrate) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity. MedChem Express
      Meropenem (trihydrate) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity.; Target: Antibacterial; Meropenem (trihydrate), a new parenteral carbapenem demonstrated increased activity as compared to imipenem against 336 strains of Neisseria gonorrhoeae, 119 strains of Haemophilus influenzae, and 110 strains of H. MedChem Express HY-13678A
      Meropenem (trihydrate) is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity.;Target: AntibacterialMeropenem (trihydrate), a new parenteral carbapenem demonstrated increased activity as compared to imipenem against 336 strains of Neisseria gonorrhoeae, 119 strains of Haemophilus influenzae, and 110 strains of H. Ceftriaxone and ciprofloxacin demonstrated activity superior to that of both carbapenems while the activity of ceftazidime was similar to that of meropenem [1]. Meropenem (trihydrate), like imipenem and various experimental penems, may overcome the resistance problems presented by Class I beta-lactamases [2]. Meropenem (trihydrate) was rapidly penetrated to the pleural effusion and was retained for a more prolonged time in the pleural effusion than in the blood of patients with accumulated pleural effusion, and it suggested the usefulness of Meropenem (trihydrate) in antibacterial therapy for patients with pleurisy causing accumulation of p MedChem Express HY-13678A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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