Jump to main content Jump to site nav

Visit the new version of ChemSpider

Try beta.chemspider

Leu-enkephalin

Molecular FormulaC₂₈H₃₇N₅O₇
Average mass555.623 Da
Monoisotopic mass555.269287 Da
ChemSpider ID406229

- 3 of 3 defined stereocentres

More details:

Names and Synonyms
Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido]-4-methylpentanoic acid

[Leu5]-Enkephalin

261-457-1 [EINECS]

58822-25-6 [RN]

Leucine Enkephalin

Leu-enkephalin [Wiki]

L-Leucine, L-tyrosylglycylglycyl-L-phenylalanyl- [ACD/Index Name]

L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucin [German] [ACD/IUPAC Name]

L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucine [ACD/IUPAC Name]

L-Tyrosylglycylglycyl-L-phénylalanyl-L-leucine [French] [ACD/IUPAC Name]

More...

N-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-leucine

RI01R707R6

Tyr-Gly-Gly-Phe-Leu-OH

([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxoethyl]amino]-1-oxoethyl]amino]-1-oxo-3-phenylpropyl]amino]-4-methylpentanoic acid

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid

(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid

(2S)-2-[[(2S)-2-[2-[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]ethanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid

(5-LEUCINE)ENKEPHALIN

(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid

(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid

[58822-25-6] [RN]

[5-Leucine]Enkephalin

[Leu 5]enkephalin

[Leu(5)]enkephalin

[Leu(5)]-enkephalin

[Leu(5)]enkephalin zwitterion

[Leu(5)]-enkephalin zwitterion

[Leu]enkephalin

14-18-6 [RN]

2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid

2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid

2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid

2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid

2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)

2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid

81678-16-2 [RN]

Dynorphin A (1-5)

Dynorphin-(1-5)

Enkephalin

Enkephalin L

enkephalin, leucine

H-Tyr(1)-Gly(2)-Gly(3)-Phe(4)-Leu(5)-OH

h-tyr-gly-gly-phe-leu-oh

ICI 114740

L-ENK

L-ENK zwitterion

Leucine-enkephalin

leucyl-enkephalin

LeuENK

Leu-ENK

Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu

Leu-enkephalin zwitterion

LEU-ENKEPHALIN[3,5-3H]

L-Leucine, N-(N-(N-(N-L-tyrosylglycyl)glycyl)-L-phenylalanyl)-

L-Tyr-Gly-Gly-L-Phe-L-Leu

L-Tyr-Gly-Gly-L-Phe-L-Leu zwitterion

L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine zwitterion

MFCD00076406

N-[(2S)-2-azaniumyl-3-(4-hydroxyphenyl)propanoyl]glycylglycyl-N-[(1S)-1-carboxylato-3-methylbutyl]-L-phenylalaninamide

N-[N-[N-(N-L-tyrosylglycyl)glycyl]-L-phenylalanyl]-L-leucine

QP1350000

tyr-gly-gly-phe-leu

Tyr-Gly-Gly-Phe-Leu zwitterion

UNII:RI01R707R6

UNII-RI01R707R6

YGGFL

Y-G-G-F-L

YGGFL zwitterion

Less...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

61885_FLUKA [DBID]

AIDS030267 [DBID]

AIDS-030267 [DBID]

NSC350588 [DBID]

Experimental data
Predicted - ACD/Labs
Predicted - ChemAxon
Predicted - Mcule

Experimental Physico-chemical Properties
- Experimental Solubility:
  
  Soluble to 1 mg/ml in water Tocris Bioscience 1889

Miscellaneous

Chemical Class:

Bio Activity:

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density:	1.3±0.1 g/cm³
Boiling Point:	998.8±65.0 °C at 760 mmHg
Vapour Pressure:	0.0±0.3 mmHg at 25°C
Enthalpy of Vaporization:	152.6±3.0 kJ/mol
Flash Point:	557.8±34.3 °C
Index of Refraction:	1.587
Molar Refractivity:	146.5±0.3 cm³
#H bond acceptors:	12
#H bond donors:	8
#Freely Rotating Bonds:	15
#Rule of 5 Violations:	3

ACD/LogP:	2.08
ACD/LogD (pH 5.5):	-1.12
ACD/BCF (pH 5.5):	1.00
ACD/KOC (pH 5.5):	1.00
ACD/LogD (pH 7.4):	-1.48
ACD/BCF (pH 7.4):	1.00
ACD/KOC (pH 7.4):	1.00
Polar Surface Area:	200 Å²
Polarizability:	58.1±0.5 10^-24cm³
Surface Tension:	57.5±3.0 dyne/cm
Molar Volume:	436.0±3.0 cm³

Click to predict properties on the Chemicalize site

Patents	Personal Collections
Publication or Magazine Article	Web-based Article (blog or commentary)
Available Chemicals Databases	Biological Properties
Chemical Reactions	Chemical Safety Data
Drugs or Compounds in Development	Imaging Agents
Information Aggregators	Journal Publishers via MeSH
Ligand/binding/crystal Structure Databases	Metabolic Pathways
Molecular Libraries Screening Center Network	Natural Products
NIH Substance Repository	Physical Properties (including SAR/QSAR databases)
Protein 3D Structures	Spectroscopy Databases
Substance Vendors	Theoretical Properties
Toxicology/Environmental Databases	Virtual Library

Leu-enkephalin

More details:

Experimental Solubility:

Chemical Class:

Bio Activity:

Search ChemSpider:

Search Google: