ChemSpider 2D Image | Quetiapine fumarate | C46H54N6O8S2

Quetiapine fumarate

  • Molecular FormulaC46H54N6O8S2
  • Average mass883.086 Da
  • Monoisotopic mass882.344482 Da
  • ChemSpider ID4444493

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

Quetiapine fumarate [JAN] [USAN]
(2E)-2-Butendisäure --2-{2-[4-(dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol (1:2) [German] [ACD/IUPAC Name]
(2E)-But-2-endisäure--2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol(1:2)
(2E)-but-2-ènedioate de 1-dibenzo[b,f][1,4]thiazépin-11-yl-4-[2-(2-hydroxyéthoxy)éthyl]pipérazin-1-ium et de 4-dibenzo[b,f][1,4]thiazépin-11-yl-1-[2-(2-hydroxyéthoxy)éthyl]pipérazin-1-ium
111974-72-2 [RN]
1-dibenzo[b,f][1,4]thiazepin-11-yl-4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-ium 4-dibenzo[b,f][1,4]thiazepin-11-yl-1-[2-(2-hydroxyethoxy)ethyl]piperazin-1-ium (2E)-but-2-enedioate
1-Dibenzo[b,f][1,4]thiazepin-11-yl-4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-ium-4-dibenzo[b,f][1,4]thiazepin-11-yl-1-[2-(2-hydroxyethoxy)ethyl]piperazin-1-ium-(2E)-but-2-endioat
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate
2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol (2E)-but-2-enedioate (2:1) (salt)
2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol (2E)-2-butenedioate (2:1) [ACD/IUPAC Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2S3PL1B6UJ [DBID]
Seroquel XR [DBID]
D00458 [DBID]
ICI 204636 [DBID]
LS-66641 [DBID]
ZM 204636 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      5-HT Receptor MedChem Express HY-B0031
      5-HT Receptors Tocris Bioscience 4735
      5-HT<sub>2</sub> and D<sub>2</sub> antagonist (IC<sub>50</sub> values are 148 and 329 nM respectively). Lacks affinity at D<sub>1</sub> or muscarinic receptors. Atypical antipsychotic. Hello Bio HB1803
      5-HT<sub>2</sub> and D<sub>2</sub> antagonist. Atypical antipsychotic. Hello Bio HB1803
      5-HT2 Receptors Tocris Bioscience 4735
      5-HT2/D2 antagonist; atypical antipsychotic Tocris Bioscience 4735
      7-TM Receptors Tocris Bioscience 4735
      Atypical antipsychotic. Displays antagonist activity at serotonin (5-HT2) and dopamine (D2) receptors (IC50 values are 148 and 329 nM respectively). Lacks affinity at either D1 or muscarinic receptors . Tocris Bioscience 4735
      Atypical antipsychotic. Displays antagonist activity at serotonin (5-HT2) and dopamine (D2) receptors (IC50 values are 148 and 329 nM respectively). Lacks affinity at either D1 or muscarinic receptors. Tocris Bioscience 4735
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB1803
      GPCR/G protein MedChem Express HY-B0031
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0031
      Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression. MedChem Express
      Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.; IC50 value: ; Target: 5-HT Receptor; Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. MedChem Express HY-B0031
      Quetiapine fumarate is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.;IC50 value: ;Target: 5-HT ReceptorQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor. MedChem Express HY-B0031
      Receptors & Transporters/G protein coupled receptors/5-HT/5-HT<sub>2</sub> Hello Bio HB1803
      Receptors & Transporters/G protein coupled receptors/Dopamine/D2-like/D<sub>2</sub> Hello Bio HB1803

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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