ChemSpider 2D Image | Ketotifen | C23H23NO5S

Ketotifen

  • Molecular FormulaC23H23NO5S
  • Average mass425.497 Da
  • Monoisotopic mass425.129700 Da
  • ChemSpider ID4445563

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2E)-2-Butendisäure --4-(1-methyl-4-piperidinyliden)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-on (1:1) [German] [ACD/IUPAC Name]
(2E)-But-2-endisäure--4-(1-methylpiperidin-4-yliden)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-on(1:1)
10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1) [ACD/Index Name]
252-100-0 [EINECS]
34580-14-8 [RN]
4-(1-Methyl-4-piperidinylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2E)-2-butenedioate (1:1) [ACD/IUPAC Name]
4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2E)-but-2-enedioate
4-(1-Methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2E)-but-2-enedioate (1:1)
Acide (2E)-2-butènedioïque - 4-(1-méthyl-4-pipéridinylidène)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophén-10-one (1:1) [French] [ACD/IUPAC Name]
acide (2E)-but-2-ènedioïque - 4-(1-méthylpipéridin-4-ylidène)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophén-10-one (1:1)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

HBD503WORO [DBID]
UNII:HBD503WORO [DBID]
D01332 [DBID]
EU-0100706 [DBID]
K2628_SIGMA [DBID]
MLS000069701 [DBID]
Prestwick_743 [DBID]
SMR000058462 [DBID]
UNII-HBD503WORO [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Histamine Receptor antagonist;PDE inhibitor TargetMol T0994

    • Chemical Class:

      An organoammonium salt consisting of equimolar amounts of ketotifen(1+) and fumarate(1-) ions. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is a non-bronchodilator a nti-asthmatic drug. ChEBI CHEBI:31750

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 784
      An H1 receptor antagonist. Tocris Bioscience 0784, 784
      GPCR/G protein MedChem Express HY-B0157A
      GPCR/G protein; Immunology/Inflammation; MedChem Express HY-B0157A
      H1 antagonist Tocris Bioscience 0784, 784
      Histamine H1 receptor;PDE TargetMol T0994
      Histamine H1 Receptors Tocris Bioscience 784
      Histamine Receptor MedChem Express HY-B0157A
      Histamine Receptors Tocris Bioscience 784
      Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks. MedChem Express
      Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks.; Target: Histamine Receptor ; Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. MedChem Express HY-B0157A
      Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks.;Target: Histamine Receptor Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt of fumaric acid,ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds.Ketotifen relieves and prevents eye itchiness and/or irritation associated with most seasonal allergies. It starts working within minutes after administering the drops. The drug has not been studied in children under three. The mean elimination half life is 12 hours. Besides its anti-histaminic activity, it is also a functional leukotriene antagonist and a phosphod MedChem Express HY-B0157A
      Neuroscience;Metabolism TargetMol T0994

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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