ChemSpider 2D Image | L-371,257 | C28H33N3O6

L-371,257

  • Molecular FormulaC28H33N3O6
  • Average mass Da
  • Monoisotopic mass Da
  • ChemSpider ID5293524

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-(1-{4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl}-4-piperidinyl)-1,4-dihydro-2H-3,1-benzoxazin-2-on [German] [ACD/IUPAC Name]
1-(1-{4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl}-4-piperidinyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one [ACD/IUPAC Name]
1-(1-{4-[(1-Acétyl-4-pipéridinyl)oxy]-2-méthoxybenzoyl}-4-pipéridinyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one [French] [ACD/IUPAC Name]
1-(1-{4-[(1-acetylpiperidin-4-yl)oxy]-2-methoxybenzoyl}piperidin-4-yl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
162042-44-6 [RN]
2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro- [ACD/Index Name]
L 371257
L-371,257 [Wiki]
[162042-44-6] [RN]
1-(1-(4-((1-acetylpiperidin-4-yl)oxy)-2-methoxybenzoyl)piperidin-4-yl)-1H-benzo[d][1,3]oxazin-2(4H)-one
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

L-371257 [DBID]
  • Experimental Physico-chemical Properties

    • Experimental Solubility:

      Soluble to 10 mM in DMSO Tocris Bioscience 2410
      Soluble to 10 mM in DMSO with gentle warming Tocris Bioscience 2410
      Soluble to 5 mM in DMSO with gentle warming Tocris Bioscience 2410
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 2410
      Oxytocin Receptors Tocris Bioscience 2410
      Peptide Receptors Tocris Bioscience 2410
      Potent and selective oxytocin receptor antagonist Tocris Bioscience 2410
      Potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. Antagonizes oxytocin-induced cont ractions in isolated rat uterine tissue (pA2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active. Tocris Bioscience 2410
      Potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Decreases length of U-87MG cell projections induced by retinoic acid (Cat.No.0695). Orally active. Tocris Bioscience 2410
      Potent, high affinity human oxytocin (OT) receptor antagonist (Ki = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active. Tocris Bioscience 2410

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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