ChemSpider 2D Image | Co 101244 | C21H28ClNO3

Co 101244

  • Molecular FormulaC21H28ClNO3
  • Average mass Da
  • Monoisotopic mass Da
  • ChemSpider ID5293623

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-[2-(4-Hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)-4-piperidinol hydrochloride (1:1) [ACD/IUPAC Name]
1-[2-(4-Hydroxyphénoxy)éthyl]-4-(4-méthylbenzyl)-4-pipéridinol, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
1-[2-(4-Hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)-4-piperidinolhydrochlorid (1:1) [German] [ACD/IUPAC Name]
1-[2-(4-Hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidin-4-ol hydrochloride (1:1)
193356-17-1 [RN]
193359-26-1 [RN]
4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-, hydrochloride (1:1) [ACD/Index Name]
Co 101244
Co 101244 hydrochloride
[193356-17-1] [RN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

Co-101244 [DBID]
PD-174494 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Glutamate (Ionotropic) Receptors Tocris Bioscience 2456
      Highly selective NR2B antagonist Tocris Bioscience 2456
      Ion Channels Tocris Bioscience 2456
      Ligand-gated Ion Channels Tocris Bioscience 2456
      Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 ?M for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neurop rotective effects in vivo and in vitro. Tocris Bioscience 2456
      Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 ?M for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro. Tocris Bioscience 2456
      Novel, potent and selective antagonist of NR2B-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 muM for NR1A/2B, NR1A/2A and NR1A/2C subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro. Tocris Bioscience 2456

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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