ChemSpider 2D Image | Adiphenine Hydrochloride | C20H26ClNO2

Adiphenine Hydrochloride

  • Molecular FormulaC20H26ClNO2
  • Average mass347.879 Da
  • Monoisotopic mass347.165222 Da
  • ChemSpider ID5560

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-(Diethylamino)ethyl 2,2-diphenylacetate hydrochloride
2-(Diethylamino)ethyl diphenylacetate hydrochloride (1:1) [ACD/IUPAC Name]
2-(Diethylamino)ethyl-diphenylacetathydrochlorid (1:1) [German] [ACD/IUPAC Name]
200-036-9 [EINECS]
228-077-8 [EINECS]
2-Diethylaminoethyl diphenylacetate hydrochloride
42B4PDY0AV
50-42-0 [RN]
6113-04-8 [RN]
Acetic acid, diphenyl-, 2- (diethylamino)ethyl ester hydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

A3649_SIGMA [DBID]
D02772 [DBID]
MLS000028404 [DBID]
NSC 129224 [DBID]
Prestwick_7 [DBID]
SMR000058354 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      AChR antagonist TargetMol T0072

    • Bio Activity:

      Adiphenine HCl is a nicotinic receptor inhibitor, used as an antispasmodic drug. MedChem Express
      Adiphenine HCl is a nicotinic receptor inhibitor, used as an antispasmodic drug.; Target: nAChR; Adiphenine decreased the frequency of ACh-induced single-channel currents. MedChem Express HY-B0379A
      Adiphenine HCl is a nicotinic receptor inhibitor, used as an antispasmodic drug.;Target: nAChRAdiphenine decreased the frequency of ACh-induced single-channel currents. adiphenine decreased cluster duration (36-fold at 100 micromolxL(-1)). adiphenine did not change amplitude but increased the decay rate (IC(50)= 15 micromolxL(-1)) [1]. Adiphenine was administered in3H-labelled form in doses of 15 u.mole/kg intravenously to male Wistar rats. Plasma and brain levels of the unchanged drug were measured [1]. The elimination of the3H -labelled compound from the plasma was monophasic with a half-life of 13 minutes. The unchanged drug was detectable in the plasma for 30 minutes after the injection. The time course of brain levels of unchanged drug paralleled that found in the plasma with a half-life of 9 to 12 minutes. In all experiments, brain and plasma levels of unchanged adiphenine correlate highly [2]. MedChem Express HY-B0379A
      Membrane Tranporter/Ion Channel MedChem Express HY-B0379A
      Membrane Tranporter/Ion Channel; Neuronal Signaling; MedChem Express HY-B0379A
      nAChR MedChem Express HY-B0379A
      Neuroscience TargetMol T0072
      Nicotinic Receptor TargetMol T0072

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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