ChemSpider 2D Image | Bupropion Hydrochloride | C13H19Cl2NO

Bupropion Hydrochloride

  • Molecular FormulaC13H19Cl2NO
  • Average mass276.202 Da
  • Monoisotopic mass275.084381 Da
  • ChemSpider ID56612

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(-)-Bupropion hydrochloride
(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride
1-(3-chlorophényl)-2-[(1,1-diméthyléthyl)amino]propan-1-one chlorhydrate
1-(3-Chlorophenyl)-2-[(2-methyl-2-propanyl)amino]-1-propanone hydrochloride (1:1) [ACD/IUPAC Name]
1-(3-Chlorophényl)-2-[(2-méthyl-2-propanyl)amino]-1-propanone, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
1-(3-Chlorphenyl)-2-[(2-methyl-2-propanyl)amino]-1-propanonhydrochlorid (1:1) [German] [ACD/IUPAC Name]
1-propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride
1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) [ACD/Index Name]
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride
2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one hydrochloride (1:1)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

B102_SIGMA [DBID]
BVF-033 [DBID]
BW 323 [DBID]
CCRIS 4693 [DBID]
D00817 [DBID]
EU-0100166 [DBID]
HSDB 6988 [DBID]
MLS000069376 [DBID]
NSC 315851 [DBID]
Prestwick_668 [DBID]
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  • Experimental Physico-chemical Properties
  • Predicted Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      AChR antagonist;Dopamine uptake inhibitor;Noradrenaline uptake inhibitor TargetMol T1150

    • Bio Activity:

      Bupropion Hydrochloride is a unicyclic, aminoketone antidepressant. MedChem Express
      Bupropion Hydrochloride is a unicyclic, aminoketone antidepressant.; Target: Dopamine Reuptake; Norepinephrine Reuptake; Bupropion is a second-generation antidepressant, with a mechanism of action different from most antidepressants, in that it is a dopamine and norepinephrine reuptake inhibitor [1]. MedChem Express HY-B0403A
      Bupropion Hydrochloride is a unicyclic, aminoketone antidepressant.;Target: Dopamine Reuptake; Norepinephrine ReuptakeBupropion is a second-generation antidepressant, with a mechanism of action different from most antidepressants, in that it is a dopamine and norepinephrine reuptake inhibitor [1]. Bupropion is approved for use in major depression and seasonal affective disorder and has demonstrated comparable efficacy to other antidepressants in clinical trials. Bupropion is also useful in augmenting a partial response to selective serotonin reuptake inhibitor antidepressants, although bupropion should not be combined with monoamine oxidase inhibitors [2]. Bupropion has demonstrated efficacy comparable to that of other antidepressants [3]. MedChem Express HY-B0403A
      Dopamine Transporters Tocris Bioscience 2831
      Neuronal AChR;Sodium-dependent dopamine transporter;Sodium-dependent noradrenaline transporter TargetMol T1150
      Neuroscience TargetMol T1150
      Neurotransmitter Transporters Tocris Bioscience 2831
      Non-selective inhibitor of dopamine and noradrenalin transporters Tocris Bioscience 2831
      Non-selective inhibitor of dopamine and noradrenalin transporters (Ki values are 1.4, 2.8 and 45 ?M for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine rec eptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo. Tocris Bioscience 2831
      Non-selective inhibitor of dopamine and noradrenalin transporters (Ki values are 1.4, 2.8 and 45 ?M for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine receptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo. Tocris Bioscience 2831
      Non-selective inhibitor of dopamine and noradrenalin transporters (Ki values are 1.4, 2.8 and 45 muM for NET, DAT and SERT transporters respectively). Also inhibits neuronal nicotinic acetylcholine receptors. Displays antidepressant activity and augments nicotine self-administration at low doses in vivo. Tocris Bioscience 2831
      Others MedChem Express HY-B0403A
      Transporters Tocris Bioscience 2831

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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