ChemSpider 2D Image | SL4250000 | C15H24ClNO

SL4250000

  • Molecular FormulaC15H24ClNO
  • Average mass269.810 Da
  • Monoisotopic mass269.154633 Da
  • ChemSpider ID58932

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

261-683-0 [EINECS]
3-(3-Ethyl-1-methyl-3-azepanyl)phenol hydrochloride (1:1) [ACD/IUPAC Name]
3-(3-Éthyl-1-méthyl-3-azépanyl)phénol, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
3-(3-Ethyl-1-methyl-3-azepanyl)phenolhydrochlorid (1:1) [German] [ACD/IUPAC Name]
3-(3-ETHYL-1-METHYLAZEPAN-3-YL)PHENOL HYDROCHLORIDE
3-(3-Ethyl-1-methylazepan-3-yl)phenol hydrochloride (1:1)
3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-phenol hydrochloride
59263-76-2 [RN]
IL-22811 hydrochloride
MEPTAZINOL HYDROCHLORIDE
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

T62FQ4ZCPA [DBID]
UNII:T62FQ4ZCPA [DBID]
B86GG845VX [DBID]
IL 22811 [DBID]
T67XX1E08N [DBID]
WY-22811 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Opioid Receptor TargetMol T0201

    • Bio Activity:

      ?1 partial agonist Tocris Bioscience 3636
      7-TM Receptors Tocris Bioscience 3636
      Centrally active opioid analgesic. Partial agonist at the ?1 opioid receptor. Also shown to inhibit acetylcholinesterase. Tocris Bioscience 3636
      Centrally active opioid analgesic. Partial agonist at the mu1 opioid receptor. Also shown to inhibit acetylcholinesterase. Tocris Bioscience 3636
      GPCR/G protein MedChem Express HY-17467A
      GPCR/G protein; Nueronal Signaling; MedChem Express HY-17467A
      Meptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic. MedChem Express
      Meptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic.; IC50 Value: < 1 nM [1]; Target: Opioid Receptor; in vitro: Meptazinol inhibits a portion of 3H-labeled opiate and opioid peptide binding quite potently, with IC50 value under 1 nM [1]. MedChem Express HY-17467A
      Meptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic.;IC50 Value: < 1 nM [1];Target: Opioid Receptor;In vitro: Meptazinol inhibits a portion of 3H-labeled opiate and opioid peptide binding quite potently, with IC50 value under 1 nM [1]. ;In vivo: Given at equianalgesic doses, morphine (3.5 mg/kg i.v.) significantly lowers the pO2 over 20 mm Hg and raises the pCO2 over 10 mm Hg as measured in arterial blood samples, whereas meptazinol (10 mg/kg i.v.) has no significant effects on either [1]. The group receiving meptazinol demonstrated no cardiovascular changes although bispectral index dropped by an additional 19% when compared to 1 min after barbiturate injection [2]. Rapid and significant levels of MEP in plasma and CSF can be achieved after nasal administration whereas the oral administration resulted in considerably lower drug concentrations [3]. MedChem Express HY-17467A
      Mu Opioid Receptors Tocris Bioscience 3636
      mu1 partial agonist Tocris Bioscience 3636
      Neuroscience TargetMol T0201
      Opioid Receptor MedChem Express HY-17467A
      Opioid Receptor TargetMol T0201
      Opioid Receptors Tocris Bioscience 3636

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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