ChemSpider 2D Image | Phenoxybenzamine Hydrochloride | C18H23Cl2NO

Phenoxybenzamine Hydrochloride

  • Molecular FormulaC18H23Cl2NO
  • Average mass340.287 Da
  • Monoisotopic mass339.115662 Da
  • ChemSpider ID5911

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-Phenoxybenzamine Hydrochloride
200-569-7 [EINECS]
63-92-3 [RN]
Bensylyt Hydrochloride
Bensylyte Hydrochloride
Benzenemethanamine, N- (2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1) [ACD/Index Name]
Benzylamine, N- (2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
Dibenyline [Trade name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AI3-52044 [DBID]
B019_SIGMA [DBID]
CCRIS 4693 [DBID]
CCRIS 506 [DBID]
D00507 [DBID]
EU-0100235 [DBID]
MLS000069374 [DBID]
NCGC00089748-02 [DBID]
NCI-C01661 [DBID]
NSC 37448 [DBID]
More...
  • Experimental Physico-chemical Properties
  • Predicted Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Adrenergic Receptor antagonist;Calmodulin inhibitor TargetMol T1158

    • Bio Activity:

      Adrenergic Receptor MedChem Express HY-B0431A
      Adrenergic Receptor;Calmodulin TargetMol T1158
      GPCR/G protein MedChem Express HY-B0431A
      GPCR/G Protein TargetMol T1158
      GPCR/G protein; MedChem Express HY-B0431A
      Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with long duration of action. MedChem Express
      Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with long duration of action.; Target: Alpha Adrenergic Receptor; Phenoxybenzamine (PB), a classical alpha-adrenergic antagonist, binds irreversibly to the alpha-adrenergic receptors (ARs). MedChem Express HY-B0431A
      Phenoxybenzamine HCl is a non-specific, irreversible alpha antagonist with long duration of action.;Target: Alpha Adrenergic ReceptorPhenoxybenzamine (PB), a classical alpha-adrenergic antagonist, binds irreversibly to the alpha-adrenergic receptors (ARs). The IC50 (100 nM) derived from the blockade of [3H]yohimbine binding by phenoxybenzamine was significantly less than the IC50 (550 nM) for the corresponding reversal by phenoxybenzamine of the effects of norepinephrine on cyclic AMP accumulation. Further studies demonstrated a rightward shift in the dose-response curves for the inhibition by norepinephrine of cyclic AMP accumulation following pretreatment with increasing phenoxybenzamine concentration [1]. MedChem Express HY-B0431A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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