ChemSpider 2D Image | guanfacine hydrochloride | C9H10Cl3N3O

guanfacine hydrochloride

  • Molecular FormulaC9H10Cl3N3O
  • Average mass282.554 Da
  • Monoisotopic mass280.988953 Da
  • ChemSpider ID64493

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

249-443-3 [EINECS]
29110-48-3 [RN]
Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1) [ACD/Index Name]
BS-100-141
Estulic [Trade name]
GUANFACINE HCL
guanfacine hydrochloride [JAN] [USAN]
Intuniv [Trade name]
MFCD00798230 [MDL number]
N-amidino-2-(2,6-dichlorophenyl) acetamide monohydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

D00606 [DBID]
EU-0100519 [DBID]
G1043_SIGMA [DBID]
MLS000069745 [DBID]
Prestwick_740 [DBID]
PubChem Substance ID 24891849 [DBID]
SMR000058453 [DBID]
SPD-503 [DBID]
UN 2811 [DBID]
UN2811 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      IRRITANT Matrix Scientific 097270

    • Target Organs:

      Adrenergic Receptor antagonist TargetMol T2150

    • Therapeutical Effect:

      antihypertensive Microsource [01505435]

    • Drug Status:

      USP, INN, BAN, JAN Microsource [01505435]

    • Compound Source:

      synthetic; BS-100-141 Microsource [01505435]

    • Bio Activity:

      ?2A agonist Tocris Bioscience 1030
      7-TM Receptors Tocris Bioscience 1030
      Adrenergic Alpha-2 Receptors Tocris Bioscience 1030
      Adrenergic Receptor MedChem Express HY-17416
      Adrenergic Receptor TargetMol T2150
      Adrenergic Receptors Tocris Bioscience 1030
      alpha2A agonist Tocris Bioscience 1030
      GPCR/G protein MedChem Express HY-17416
      GPCR/G Protein TargetMol T2150
      GPCR/G protein; MedChem Express HY-17416
      Guanfacine Hcl, an anti-hypertensive agent, is a selective ?2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over ?2B-adrenoceptors. MedChem Express HY-17416
      Selective ?2A-adrenoceptor agonist (Kd = 31 nM). Displays 60-fold selectivity over ?2B-adrenoceptors. Also available as part of the ?2-Adrenoceptor Tocriset?. Tocris Bioscience 1030
      Selective ?2A-adrenoceptor agonist (Kd = 31 nM). Displays 60-fold selectivity over ?2B-adrenoceptors. Also available as part of the ?2-Adrenoceptor Tocriset™. Tocris Bioscience 1030
      Selective alpha2A-adrenoceptor agonist (Kd = 31 nM). Displays 60-fold selectivity over alpha2B-adrenoceptors. Also available as part of the alpha2-Adrenoceptor Tocriset?. Tocris Bioscience 1030

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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