ChemSpider 2D Image | Chelerythrine chloride | C21H18ClNO4

Chelerythrine chloride

  • Molecular FormulaC21H18ClNO4
  • Average mass383.825 Da
  • Monoisotopic mass383.092438 Da
  • ChemSpider ID65262

  • Charge - Charge

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[1,3]Benzodioxolo[5,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, chloride (1:1) [ACD/Index Name]
1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium chloride [ACD/IUPAC Name]
1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-iumchlorid [German] [ACD/IUPAC Name]
1,2-Dimethoxy-12-methyl[1,3]dioxolo[4,5]benzo[1,2-c]phenanthridin-12-iumchlorid
223-444-9 [EINECS]
3895-92-9 [RN]
Chelerythrine (chloride)
chelerythrine chlorid [German]
Chelerythrine chloride
Chelerythrine, chloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

7IC98TZ0PZ [DBID]
C2932_SIGMA [DBID]
EU-0100241 [DBID]
NSC 36405 [DBID]
NSC36405 [DBID]
NSC646662 [DBID]
UNII:7IC98TZ0PZ [DBID]
UNII-7IC98TZ0PZ [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      Phosphorylation EU-OpenScreen [C 2932]

    • Bio Activity:

      Cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, inc luding antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 ?M) or Bad proteins an d stimulates apoptosis. Tocris Bioscience 1330
      Cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 ?M) or Bad proteins and stimulates apoptosis. Tocris Bioscience 1330
      Cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC50 = 1.5 muM) or Bad proteins and stimulates apoptosis. Tocris Bioscience 1330
      Cell-permeable protein kinase C inhibitor Tocris Bioscience 1330
      Chelerythrine is potent, cell-permeable inhibitor of protein kinase C (IC50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. MedChem Express http://www.medchemexpress.com/chelerythrine-chloride.html, HY-12048
      Enzymes Tocris Bioscience 1330
      Kinases Tocris Bioscience 1330
      PKC MedChem Express HY-12048
      Protein Kinase C Tocris Bioscience 1330
      TGF-beta/Smad MedChem Express HY-12048
      TGF-beta/Smad; MedChem Express HY-12048

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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