ChemSpider 2D Image | 4-[(2S)-4-Acryloyl-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridinyl)pyrido[2,3-d]pyrimidin-2(1H)-one | C30H30F2N6O3

4-[(2S)-4-Acryloyl-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridinyl)pyrido[2,3-d]pyrimidin-2(1H)-one

  • Molecular FormulaC30H30F2N6O3
  • Average mass560.594 Da
  • Monoisotopic mass560.234741 Da
  • ChemSpider ID72380148
  • defined stereocentres - 1 of 1 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4-[(2S)-4-Acryloyl-2-methyl-1-piperazinyl]-6-fluor-7-(2-fluor-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridinyl)pyrido[2,3-d]pyrimidin-2(1H)-on [German] [ACD/IUPAC Name]
4-[(2S)-4-Acryloyl-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridinyl)pyrido[2,3-d]pyrimidin-2(1H)-one [ACD/IUPAC Name]
4-[(2S)-4-Acryloyl-2-méthyl-1-pipérazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphényl)-1-(2-isopropyl-4-méthyl-3-pyridinyl)pyrido[2,3-d]pyrimidin-2(1H)-one [French] [ACD/IUPAC Name]
Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- [ACD/Index Name]
(1R)-4-((S)-4-Acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
2252403-56-6 [RN]
2296729-00-3 [RN]
2296729-66-1 [RN]
AMG 510
AMG-510
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Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.4±0.1 g/cm3
Boiling Point: 730.5±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.5 mmHg at 25°C
Enthalpy of Vaporization: 110.4±3.0 kJ/mol
Flash Point: 395.6±35.7 °C
Index of Refraction: 1.651
Molar Refractivity: 150.5±0.5 cm3
#H bond acceptors: 9
#H bond donors: 1
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 1
ACD/LogP: 2.52
ACD/LogD (pH 5.5): 1.94
ACD/BCF (pH 5.5): 10.69
ACD/KOC (pH 5.5): 106.23
ACD/LogD (pH 7.4): 1.59
ACD/BCF (pH 7.4): 4.86
ACD/KOC (pH 7.4): 48.31
Polar Surface Area: 102 Å2
Polarizability: 59.6±0.5 10-24cm3
Surface Tension: 47.3±7.0 dyne/cm
Molar Volume: 411.9±7.0 cm3

Click to predict properties on the Chemicalize site






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