ChemSpider 2D Image | AMISULPRIDE HYDROCHLORIDE | C17H28ClN3O4S

AMISULPRIDE HYDROCHLORIDE

  • Molecular FormulaC17H28ClN3O4S
  • Average mass405.940 Da
  • Monoisotopic mass405.148895 Da
  • ChemSpider ID8222460

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride (1:1) [ACD/IUPAC Name]
4-Amino-N-[(1-éthyl-2-pyrrolidinyl)méthyl]-5-(éthylsulfonyl)-2-méthoxybenzamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
81342-13-4 [RN]
AMISULPRIDE HYDROCHLORIDE
AMISULPRIDE HYDROCHLORIDE, (R)-
AMISULPRIDE HYDROCHLORIDE, (S)-
Benzamide, 4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-, hydrochloride (1:1) [ACD/Index Name]
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
81342-13-4 (HCl)
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

TC6N8QV7QO [DBID]
UNII:TC6N8QV7QO [DBID]
3EFP1M282K [DBID]
LC5CC5PB4Z [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Amisulpride Hcl(DAN 2163 Hcl) is an antipsychotic drug, which is a selective dopamine antagonist (Ki=2.8 nM D2 receptor; Ki=3.2 nM D3 receptor). MedChem Express
      Amisulpride Hcl(DAN 2163 Hcl) is an antipsychotic drug, which is a selective dopamine antagonist (Ki=2.8 nM D2 receptor; Ki=3.2 nM D3 receptor).; Target: D2/D3 receptor; Amisulpride hydrochloride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. MedChem Express HY-14545A
      Amisulpride Hcl(DAN 2163 Hcl) is an antipsychotic drug, which is a selective dopamine antagonist (Ki=2.8 nM D2 receptor; Ki=3.2 nM D3 receptor).;Target: D2/D3 receptorAmisulpride hydrochloride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. In small doses it is also used to treat depression. Amisulpride hydrochloride functions primarily as a D2 and D3 receptor antagonist. It has high affinity for these receptors with dissociation constants of 2.8 nM and 3.2 nM, respectively [1]. At low doses (< or = 10 mg/kg) amisulpride hydrochloride preferentially blocks presynaptic dopamine autoreceptors that control dopamine synthesis and release in the rat, whereas at higher doses (40-80 mg/kg) postsynaptic dopamine D2 receptor occupancy and antagonism is apparent. In contrast, haloperidol is active in all of these paradigms within the same dose range. Amisulpride hydrochloride preferentially inhibits in vivo binding of the D2/ MedChem Express HY-14545A
      Dopamine Receptor MedChem Express HY-14545A
      GPCR/G protein MedChem Express HY-14545A
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-14545A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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