ChemSpider 2D Image | Methanesulfonic acid | C40H41F6N3O5S

Methanesulfonic acid

  • Molecular FormulaC40H41F6N3O5S
  • Average mass789.826 Da
  • Monoisotopic mass789.267090 Da
  • ChemSpider ID9449335

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

202914-84-9 [RN]
9H-Fluorene-9-carboxamide, N-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-, methanesulfonate (1:1) [ACD/Index Name]
Acide méthanesulfonique - N-(2,2,2-trifluoroéthyl)-9-{4-[4-({[4'-(trifluorométhyl)-2-biphénylyl]carbonyl}amino)-1-pipéridinyl]butyl}-9H-fluorène-9-carboxamide (1:1) [French] [ACD/IUPAC Name]
lomitapide mesylate [USAN]
Methanesulfonic acid [ACD/Index Name] [ACD/IUPAC Name] [Wiki]
Methansulfonsäure --N-(2,2,2-trifluorethyl)-9-{4-[4-({[4'-(trifluormethyl)-2-biphenylyl]carbonyl}amino)-1-piperidinyl]butyl}-9H-fluoren-9-carboxamid (1:1) [German] [ACD/IUPAC Name]
N-(2,2,2-trifluoroethyl)-9-(4-{4-[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido]piperidin-1-yl}butyl)-9H-fluorene-9-carboxamide
N-(2,2,2-trifluoroethyl)-9-(4-{4-[4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido]piperidin-1-yl}butyl)-9H-fluorene-9-carboxamide; methanesulfonic acid
N-(2,2,2-Trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)-2-biphenylyl]carbonyl}amino)-1-piperidinyl]butyl}-9H-fluorene-9-carboxamide methanesulfonate (1:1) [ACD/IUPAC Name]
X4S83CP54E
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AEGR-733 [DBID]
BMS-201038 [DBID]
BMS-201038-04 [DBID]
BMS 201038-04 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Target Organs:

      MTP inhibitor TargetMol T2545
    • Chemical Class:

      A methanesulfonate (mesylate) salt prepared from equimolar amounts of lomitapide and methanesulfonic acid. Used as a complement to a low-fat diet and other lipid-lowering treatments in patients with h omozygous familial hypercholesterolemia. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:72299, CHEBI:72299
    • Bio Activity:

      Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. MedChem Express
      Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.; IC50 value: 8 nM [1]; Target: MTP inhibitor; Lomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. MedChem Express HY-14668
      Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.;IC50 value: 8 nM [1];Target: MTP inhibitorLomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant to HMG-CoA reductase inhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain. MedChem Express HY-14668
      Metabolism TargetMol T2545
      MTP TargetMol T2545
      Others MedChem Express HY-14668

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site






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