ChemSpider 2D Image | DG-041 | C23H15Cl4FN2O3S2

DG-041

  • Molecular FormulaC23H15Cl4FN2O3S2
  • Average mass592.317 Da
  • Monoisotopic mass589.926208 Da
  • ChemSpider ID9471267

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2E)-3-[1-(2,4-Dichlorbenzyl)-5-fluor-3-methyl-1H-indol-7-yl]-N-[(4,5-dichlor-2-thienyl)sulfonyl]acrylamid [German] [ACD/IUPAC Name]
(2E)-3-[1-(2,4-Dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]acrylamide [ACD/IUPAC Name]
(2E)-3-[1-(2,4-Dichlorobenzyl)-5-fluoro-3-méthyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thiényl)sulfonyl]acrylamide [French] [ACD/IUPAC Name]
1844425CLP
2-Propenamide, 3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-, (2E)- [ACD/Index Name]
3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-7-indolyl]-N-[(4,5-dichloro-2-thiophenyl)sulfonyl]-2-propenamide
861238-35-9 [RN]
DG-041
(E)-3-(1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-1H-indol-7-yl)-N-((4,5-dichlorothiophen-2-yl)sulfonyl)acrylamide
(E)-3-[1-(2,4-dichlorobenzyl)-5-fluoro-3-methyl-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]acrylamide
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 6240
      Potent and selective EP3 antagonist (IC50 = 4.6 nM). Inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability. Does not affect bleeding time in rats. Antiplatelet and antithrombotic. Tocris Bioscience 6240
      Potent and selective EP3 antagonist; antiplatelet and antithrombotic Tocris Bioscience 6240
      Prostanoid Receptors Tocris Bioscience 6240

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.6±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.681
Molar Refractivity: 141.9±0.5 cm3
#H bond acceptors: 5
#H bond donors: 1
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 2
ACD/LogP: 8.56
ACD/LogD (pH 5.5): 5.78
ACD/BCF (pH 5.5): 5777.57
ACD/KOC (pH 5.5): 5716.21
ACD/LogD (pH 7.4): 5.47
ACD/BCF (pH 7.4): 2796.30
ACD/KOC (pH 7.4): 2766.61
Polar Surface Area: 105 Å2
Polarizability: 56.2±0.5 10-24cm3
Surface Tension: 54.9±7.0 dyne/cm
Molar Volume: 375.2±7.0 cm3

Click to predict properties on the Chemicalize site


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