ChemSpider 2D Image | Talabostat mesylate | C10H23BN2O6S

Talabostat mesylate

  • Molecular FormulaC10H23BN2O6S
  • Average mass310.175 Da
  • Monoisotopic mass310.136993 Da
  • ChemSpider ID9697235

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[(2R)-1-(L-Valyl)-2-pyrrolidinyl]boronic acid methanesulfonate (1:1) [ACD/IUPAC Name]
[(2R)-1-[(2S)-2-AMINO-3-METHYLBUTANOYL]PYRROLIDIN-2-YL]BORONIC ACID; METHANESULFONIC ACID
150080-09-4 [RN]
Acide méthanesulfonique - acide [(2R)-1-(L-valyl)-2-pyrrolidinyl]boronique (1:1) [French] [ACD/IUPAC Name]
Boronic acid, B-[(2R)-1-[(2S)-2-amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-, methanesulfonate (1:1) [ACD/Index Name]
Methansulfonsäure --[(2R)-1-(L-valyl)-2-pyrrolidinyl]borsäure (1:1) [German] [ACD/IUPAC Name]
Talabostat (mesylate)
Talabostat mesylate [USAN]
V8ZG4Y1B51
[(2R)-1-[(2S)-2-amino-3-methyl-1-oxobutyl]-2-pyrrolidinyl]boronic acid
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

PT-100 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      DPP4 MedChem Express HY-13233A
      Metabolism/Protease MedChem Express HY-13233A
      Metabolism/Protease; MedChem Express HY-13233A
      Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein. MedChem Express
      Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein.; IC50 value: 1 nM [1]; Tareget: DPP4; By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. MedChem Express HY-13233A
      Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein.;IC50 value: 1 nM [1];Tareget: DPP4By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. MedChem Express HY-13233A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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