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Dasatinib

Molecular FormulaC₂₂H₂₈ClN₇O₃S
Average mass506.021 Da
Monoisotopic mass505.166290 Da
ChemSpider ID9715466

More details:

Names and Synonyms
Database ID(s)

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-, hydrate (1:1) [ACD/Index Name]

863127-77-9 [RN]

Dasatinib [INN] [USAN] [Wiki]

Dasatinib monohydrate

N-(2-Chlor-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazol-5-carboxamidhydrat (1:1) [German] [ACD/IUPAC Name]

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide hydrate (1:1) [ACD/IUPAC Name]

N-(2-Chloro-6-méthylphényl)-2-({6-[4-(2-hydroxyéthyl)-1-pipérazinyl]-2-méthyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide, hydrate (1:1) [French] [ACD/IUPAC Name]

N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide hydrate

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide hydrate (1:1)

RBZ1571X5H

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[302962-49-8] [RN]

[863127-77-9] [RN]

302962-49-8 [RN]

863127-77-9 (hydrate)

D06414

Dasatinib (monohydrate)

Dasatinib (USAN)

Dasatinib Hydrate

Dasatinib hydrate (JAN)

dasatinib monohydrate

dasatinib.H2O

GS-4248

hydrate

MFCD08704581 [MDL number]

MFCD11046566 [MDL number]

N-(2-chloro-6-methylphenyl)[2-({6-[4-(2-hydroxyethyl)piperazinyl]-2-methylpyrimidin-4-yl}amino)(1,3-thiazol-5-yl)]carboxamide, oxamethane

N-(2-chloro-6-methylphenyl)-2-((6-(4-(2- hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate

N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-5-thiazolecarboxamide monohydrate

N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate

N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide--water (1/1)

N-(2-CHLORO-6-METHYLPHENYL)-2-[[6-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-METHYL-4-PYRIMIDINYL]AMINO]-5-THIAZOLE, CARBOXAMIDE MONOHYDRATE

N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide hydrate

N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrate

N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide and hydrate

N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide hydrate

N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide hydrate

N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide,hydrate

N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]thiazole-5-carboxamide hydrate

Sprycel [Trade name]

SPRYCEL (TN)

UNII:RBZ1571X5H

UNII-RBZ1571X5H

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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BMS-354825-03 [DBID]

BMS 35482503 [DBID]

BMS 354825-03 [DBID]

BMS-354825 Monohydrate [DBID]

QA-3341 [DBID]

Experimental data
Predicted - ACD/Labs
Predicted - ChemAxon

Miscellaneous

Target Organs:

Bcr-Abl inhibitor;EPHA antagonist;Mast/stem cell GFR Kit; Src inhibitor TargetMol T1448L

Chemical Class:

Bio Activity:

Abl, Lck, Yes, Fyn;EPHA;Mast/stem cell GFR Kit;Src TargetMol T1448L

Tyrosine Kinase/Adaptors TargetMol T1448L

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Density:
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#H bond donors:
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ACD/LogP:
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ACD/BCF (pH 5.5):
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ACD/LogD (pH 7.4):
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Click to predict properties on the Chemicalize site

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Dasatinib

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