ChemSpider 2D Image | Vialinin A | C34H26O8

Vialinin A

  • Molecular FormulaC34H26O8
  • Average mass562.565 Da
  • Monoisotopic mass562.162781 Da
  • ChemSpider ID9737907

More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4,4'',5',6'-Tetrahydroxy-1,1':4',1''-terphenyl-2',3'-diyl bis(phenylacetate) [ACD/IUPAC Name]
4,4'',5',6'-Tetrahydroxy-1,1':4',1''-terphenyl-2',3'-diyl-bis(phenylacetat) [German] [ACD/IUPAC Name]
858134-23-3 [RN]
Benzeneacetic acid, 4,4'',5',6'-tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl ester [ACD/Index Name]
Bis(phénylacétate) de 4,4'',5',6'-tétrahydroxy-1,1':4',1''-terphényl-2',3'-diyle [French] [ACD/IUPAC Name]
Vialinin A
[3,4-dihydroxy-2,5-bis(4-hydroxyphenyl)-6-(2-phenylacetyl)oxyphenyl] 2-phenylacetate
[858134-23-3]
10.1016/j.bmcl.2013.05.093
4,?4?,?5?,?6?-?TETRAHYDROXY[1,?1?:4?,?1?-?TERPHENYL]-?2?,?3?-?DIYL ESTER BENZENEACETIC ACID
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Deubiquitinating Enzymes Tocris Bioscience 4988
      Enzymes Tocris Bioscience 4988
      Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 ?M, respectively). Shows no signific ant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF-? (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells. Tocris Bioscience 4988
      Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 ?M, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF-? (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells. Tocris Bioscience 4988
      Inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 muM, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF-alpha (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells. Tocris Bioscience 4988
      Inhibitor of USP4 and USP5/IsoT Tocris Bioscience 4988
      Proteases Tocris Bioscience 4988

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.4±0.1 g/cm3
Boiling Point: 846.9±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±3.3 mmHg at 25°C
Enthalpy of Vaporization: 127.3±3.0 kJ/mol
Flash Point: 277.1±27.8 °C
Index of Refraction: 1.677
Molar Refractivity: 154.6±0.3 cm3
#H bond acceptors: 8
#H bond donors: 4
#Freely Rotating Bonds: 10
#Rule of 5 Violations: 1
ACD/LogP: 4.58
ACD/LogD (pH 5.5): 4.84
ACD/BCF (pH 5.5): 2826.51
ACD/KOC (pH 5.5): 10252.53
ACD/LogD (pH 7.4): 4.59
ACD/BCF (pH 7.4): 1553.01
ACD/KOC (pH 7.4): 5633.20
Polar Surface Area: 134 Å2
Polarizability: 61.3±0.5 10-24cm3
Surface Tension: 64.1±3.0 dyne/cm
Molar Volume: 410.4±3.0 cm3

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