ChemSpider 2D Image | Delafloxacin meglumine | C25H29ClF3N5O9

Delafloxacin meglumine

  • Molecular FormulaC25H29ClF3N5O9
  • Average mass635.974 Da
  • Monoisotopic mass635.160583 Da
  • ChemSpider ID9752981

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
1-(6-Amino-3,5-difluor-2-pyridinyl)-8-chlor-6-fluor-7-(3-hydroxy-1-azetidinyl)-4-oxo-1,4-dihydro-3-chinolincarbonsäure --1-desoxy-1-(methylamino)-D-glucitol (1:1) [German] [ACD/IUPAC Name]
1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-7-(3-hydroxy-1-azetidinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1) [ACD/IUPAC Name]
352458-37-8 [RN]
3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-, compd. with D-glucitol, 1-deoxy-1-(methylamino)- (1:1) [ACD/Index Name]
Acide 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-7-(3-hydroxy-1-azétidinyl)-4-oxo-1,4-dihydro-3-quinoléinecarboxylique - 1-désoxy-1-(méthylamino)-D-glucitol (1:1) [French] [ACD/IUPAC Name]
Delafloxacin (MegluMine)
Delafloxacin meglumine [USAN]
N7V53U4U4T
(2R,3R,4R,5S)-2,3,4,5-tetrahydroxy-6-(methylamino)hexyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

ABT-492 [DBID]
RX-3341 [DBID]
WQ-3034 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Antibacterial MedChem Express HY-14814A
      Anti-infection MedChem Express HY-14814A
      Anti-infection; MedChem Express HY-14814A
      Delafloxacin meglumine is a fluoroquinolone antibiotic agent.; IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1]; Target: Antibacterial; ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.; in vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. MedChem Express HY-14814A
      Delafloxacin meglumine is a fluoroquinolone antibiotic agent.;IC50 Value: MICs ranging from 0.0078 to 0.125 micro g/ml for levofloxacin-resistant Streptococcus pneumoniae strains [1];Target: AntibacterialABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms.;In vitro: ABT-492 exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015 [2]. ABT-492 was as active as trovafloxacin against Chlamydia trachomatis, indicating good intracellular penetration and antibacterial activity [3].;In viv MedChem Express HY-14814A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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