Found 1 result

Search term: LPWONNPEPDHEAI-GJZGRUSLSA-N (Found by InChIKey (full match))
ChemSpider 2D Image | TFB-TBOA | C19H17F3N2O6

TFB-TBOA

  • Molecular FormulaC19H17F3N2O6
  • Average mass426.343 Da
  • Monoisotopic mass426.103882 Da
  • ChemSpider ID23014380

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(3S)-3-[(3-{[4-(Trifluormethyl)benzoyl]amino}benzyl)oxy]-L-asparaginsäure [German] [ACD/IUPAC Name]
(3S)-3-[(3-{[4-(Trifluoromethyl)benzoyl]amino}benzyl)oxy]-L-aspartic acid [ACD/IUPAC Name]
480439-73-4 [RN]
Acide (3S)-3-[(3-{[4-(trifluorométhyl)benzoyl]amino}benzyl)oxy]-L-aspartique [French] [ACD/IUPAC Name]
L-Aspartic acid, 3-[[3-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methoxy]-, (3S)- [ACD/Index Name]
TFB-TBOA
(2{s},3{s})-2-Azanyl-3-[[3-[[4-(Trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic Acid
(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
[480439-73-4] [RN]
7O9
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
UN2811 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold for research purposes under license from Suntory Ltd. Tocris Bioscience 2532

    • Bio Activity:

      Glutamate Transporters Tocris Bioscience 2532
      High affinity EAAT1 and EAAT2 blocker Tocris Bioscience 2532
      Neurotransmitter Transporters Tocris Bioscience 2532
      Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Has no effect on EAAT4 and EAAT5, or a wide rang e of neuronal receptors and transporters. Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM). Induces severe convulsions in vivo. Tocris Bioscience 2532
      Potent and selective glial glutamate transporter EAAT1 and EAAT2 inhibitor (IC50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Has no effect on EAAT4 and EAAT5, or a wide range of neuronal receptors and transporters. Attenuates glutamate-stimulated intracellular Na+ elevation in astrocytes in vitro (IC50 = 43 nM). Induces severe convulsions in vivo. Tocris Bioscience 2532
      Transporters Tocris Bioscience 2532

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.5±0.1 g/cm3
Boiling Point: 513.6±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.4 mmHg at 25°C
Enthalpy of Vaporization: 82.7±3.0 kJ/mol
Flash Point: 264.4±30.1 °C
Index of Refraction: 1.603
Molar Refractivity: 97.6±0.3 cm3
#H bond acceptors: 8
#H bond donors: 5
#Freely Rotating Bonds: 9
#Rule of 5 Violations: 1
ACD/LogP: 3.97
ACD/LogD (pH 5.5): -1.06
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -1.10
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 139 Å2
Polarizability: 38.7±0.5 10-24cm3
Surface Tension: 58.8±3.0 dyne/cm
Molar Volume: 284.2±3.0 cm3

Click to predict properties on the Chemicalize site


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