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Found 1 result

Search term: MHFRGQHAERHWKZ-HHHXNRCGSA-N (Found by InChIKey (full match))

Edelfosine

Molecular FormulaC₂₇H₅₈NO₆P
Average mass Da
Monoisotopic mass Da
ChemSpider ID5293425

- 1 of 1 defined stereocentres

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2R)-2-Methoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate [ACD/IUPAC Name]

(2R)-2-Methoxy-3-(octadecyloxy)propyl-2-(trimethylammonio)ethylphosphat [German] [ACD/IUPAC Name]

(R)-edelfosine

2-O-methyl PAF C-18

77286-66-9 [RN]

Edelfosine [INN] [Wiki]

ET-18-OCH3

Ethanaminium, 2-[[hydroxy[(2R)-2-methoxy-3-(octadecyloxy)propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt [ACD/Index Name]

MFCD00063527 [MDL number]

Phosphate de (2R)-2-méthoxy-3-(octadécyloxy)propyle et de 2-(triméthylammonio)éthyle [French] [ACD/IUPAC Name]

More...

(+)-(R)-Edelfosine

(+)-(R)-ET-18-OMe

(2R)-2-methoxy-3-(octadecyloxy)propyl [2-(trimethylazaniumyl)ethyl] phosphate

(2R)-2-methoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate

(7R)-4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium-4-oxide

(R)-2-Methoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

[(2S)-2-methoxy-3-octadecoxypropyl] 2-trimethylammonioethyl phosphate

[(2S)-2-methoxy-3-octadecoxy-propyl] 2-trimethylammonioethyl phosphate

[(2S)-2-methoxy-3-octadecoxypropyl] 2-trimethylazaniumylethyl phosphate

[(2S)-2-methoxy-3-octadecoxy-propyl] 2-trimethylazaniumylethyl phosphate

[(2S)-2-methoxy-3-stearyloxy-propyl] 2-trimethylammonioethyl phosphate

[77286-66-9] [RN]

{2-[Hydroxy-(2-methoxy-3-octadecyloxy-propoxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium

1-octadecyl-2-methyl-sn-glycero-3-phosphocholine

1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine

1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine

2-methyl-3-octadecyl-sn-glycero-3-phosphocholine

2-O-METHYL-PAF C-18

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (S)-

3,5,9-trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7R-methoxy-N,N,N-trimethyl-4-oxide

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-N,N,N-trimethyl-,inner salt,4-oxide

ET 18-OCH3

ET-18-OCH3 |

NSC 631156 |

PC(O-18:0/O-1:0)

PC(O-18:0/O-1:0[S])

sn-ET-18-OCH3

UNII-1Y6SNA8L5S

YK0718000

Less...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

LZ198HY9OE [DBID]

EU-0100430 [DBID]

LMGP01040049 [DBID]

Lopac-E-1779 [DBID]

NCGC00015402-01 [DBID]

O9262_SIGMA [DBID]

Experimental data
Predicted - ACD/Labs
Predicted - ChemAxon
Predicted - Mcule

References
- Fema No:
  
  -18 Hello Bio [HB0278]

Experimental Physico-chemical Properties

Bio Activity:

Biochemicals & small molecules/Antagonists & inhibitors Hello Bio [HB0278]

Enzymes Tocris Bioscience 3022

Enzymes/Esterase/Phospholipase Hello Bio [HB0278]

Esterases Tocris Bioscience 3022

Phospholipases Tocris Bioscience 3022

Selective phosphatidylinositol phospholipase (PLC) inhibitor (IC<sub>50</sub> = 9.6 µM). Inhibits mitochondrial respiration, ERK1/2 and p38 MAPK. Also activates Fas/CD95 death receptor. Displays antitumor and apoptosis -inducing properties. Hello Bio [HB0278]

Selective PI-PLC inhibitor, also PAF receptor agonist Tocris Bioscience 3022

Selective PLC inhibitor Hello Bio [HB0278]

Synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50= 9.6 ?M in fibroblasts and adenocarcinoma cells). Also acts as an agonist at platelet-activating factor (PAF) receptors. Antitumor lipid; selectively induces apoptosis in tumor cells, sparing normal cells. Tocris Bioscience 3022

Synthetic lysophospholipid analog that selectively inhibits phosphatidylinositol phospholipase C (IC50= 9.6 muM in fibroblasts and adenocarcinoma cells). Also acts as an agonist at platelet-activating factor (PAF) receptors. Antitumor lipid; selectively induces apoptosis in tumor cells, sparing normal cells. Tocris Bioscience 3022

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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Index of Refraction:
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ACD/LogP:
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ACD/KOC (pH 5.5):
ACD/LogD (pH 7.4):
ACD/BCF (pH 7.4):
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Polar Surface Area:
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Click to predict properties on the Chemicalize site

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Found 1 result

Edelfosine

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