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Search term: OQZQSRICUOWBLW-UHFFFAOYSA-N (Found by InChIKey (full match))
ChemSpider 2D Image | 2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride | C19H18ClNO3

2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride

  • Molecular FormulaC19H18ClNO3
  • Average mass343.804 Da
  • Monoisotopic mass343.097534 Da
  • ChemSpider ID10131837

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-one hydrochloride (1:1) [ACD/IUPAC Name]
2-(4-Morpholinyl)-8-phényl-4H-chromén-4-one, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-onhydrochlorid (1:1) [German] [ACD/IUPAC Name]
2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one hydrochloride
2-(Morpholin-4-yl)-8-phenyl-4H-chromen-4-one hydrochloride (1:1)
2-(MORPHOLIN-4-YL)-8-PHENYLCHROMEN-4-ONE HYDROCHLORIDE
2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride
4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-, hydrochloride (1:1) [ACD/Index Name]
934389-88-5 [RN]
[934389-88-5] [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

EU-0100710 [DBID]
L9908_SIGMA [DBID]
LY 294002 [DBID]
LY 294002 hydrochloride [DBID]
LY294002 [DBID] [Wiki]
  • References
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      <p>LY 294002 hydrochloride is a competitive and reversible PI3-Kinase inhibitor (IC<sub>50</sub> values are 0.5, 0.6, 0.3 and 3.8 &micro;M at p110&alpha; (PI3-K&alpha;), p110&beta; (PI3-K&beta;), p110&delta; (PI3-K&delta;) and p110&gamma; (PI3-K&gamma;) respectively). It also shows activity at a range of other PI3-K related kinases and other targets.</p> <p><br />LY 294002 additionally inhibits growth of many tumor types and induces apoptosis. It also suppresses proliferation of mESCs (<span>mouse embryonic stem cells).</span></p> Hello Bio HB2266
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB2266
      Cell process/Stem cells/Proliferation Hello Bio HB2266
      Enzymes Tocris Bioscience 1130
      Enzymes/Kinase/PI-3K Hello Bio HB2266
      Kinases Tocris Bioscience 1130
      PI 3-Kinase Tocris Bioscience 1130
      PI3-K inhibitor. Suppresses mESC proliferation. Hello Bio HB2266
      Prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 ?M for PI 3-K?, PI 3-K?, PI 3-K? and PI 3-K? respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 a nd PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes. Negativ e control LY 303511 (Cat. No. 2418) also available. Tocris Bioscience 1130
      Prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 ?M for PI 3-K?, PI 3-K?, PI 3-K? and PI 3-K? respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 and PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes. Negative control LY 303511 (Cat. No. 2418) also available. Tocris Bioscience 1130
      Prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 muM for PI 3-Kbeta, PI 3-Kalpha, PI 3-Kdelta and PI 3-Kgamma respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 and PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes. Negative Control also available. View R&D Systems' research poster featuring LY 294002 hydrochloride. Tocris Bioscience 1130
      Prototypical PI 3-kinase inhibitor (IC50 values are 0.31, 0.73, 1.06 and 6.60 muM for PI 3-Kbeta, PI 3-Kalpha, PI 3-Kdelta and PI 3-Kgamma respectively). Also inhibits other kinases including, CK2, mTOR, PLK1, PIM1 and PIM3. Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo. Suppresses proliferation of mESCs. Inhibits autophagic sequestration in rat hepatocytes. Negative control LY 303511 (Cat. No. 2418) also available. Tocris Bioscience 1130
      Prototypical PI 3-kinase inhibitor; also inhibits other kinases Tocris Bioscience 1130

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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