Found 1 result

Search term: UNMJSSQZDQBGDS-OCFLPWLCSA-N (Found by InChIKey (full match))
ChemSpider 2D Image | N~2~-{[4-(2-Naphthoylamino)phenyl]acetyl}-L-arginyl-L-isoleucyl-L-alpha-aspartyl-N-[(2S)-2-methylbutyl]-L-argininamide | C46H66N12O8

N2-{[4-(2-Naphthoylamino)phenyl]acetyl}-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-methylbutyl]-L-argininamide

  • Molecular FormulaC46H66N12O8
  • Average mass915.092 Da
  • Monoisotopic mass914.512634 Da
  • ChemSpider ID23152354

  • defined stereocentres - 6 of 6 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

L-Argininamide, N2-[2-[4-[(2-naphthalenylcarbonyl)amino]phenyl]acetyl]-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-methylbutyl]- [ACD/Index Name]
N2-{[4-(2-Naphthoylamino)phenyl]acetyl}-L-arginyl-L-isoleucyl-L-α-asparagyl-N-[(2S)-2-methylbutyl]-L-argininamid [German] [ACD/IUPAC Name]
N2-{[4-(2-Naphthoylamino)phenyl]acetyl}-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-methylbutyl]-L-argininamide [ACD/IUPAC Name]
N2-{2-[4-(2-Naphtoylamino)phényl]acétyl}-L-arginyl-L-isoleucyl-L-α-aspartyl-N-[(2S)-2-méthylbutyl]-L-argininamide [French] [ACD/IUPAC Name]
N5-(diaminomethylidene)-N2-({4-[(naphthalen-2-ylcarbonyl)amino]phenyl}acetyl)-L-ornithyl-L-isoleucyl-L-α-aspartyl-N5-(diaminomethylidene)-N-[(2S)-2-methylbutyl]-L-ornithinamide
(S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbamoyl)-butyl]-3-{(2S,3S)-2-[(S)-5-guanidino-2-(2-{4-[(naphthalene-2-carbonyl)-amino]-phenyl}-acetylamino)-pentanoylamino]-3-methyl-pentanoylamino}-succinamic acid
[124833-45-0] [RN]
124833-45-0 [RN]
CHEMBL58588

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AP 811 [DBID]
CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzyme-Linked Receptors Tocris Bioscience 5498
      High affinity, selective ANP clearance receptor (NPR3) antagonist (Ki = 0.45 nM). Exhibits >20,000-fold selectivity for NPR3 over NPR1. Inhibits ANP-stimulated Na+/K+ pump activity in rabbit ventricul ar cardiomyocytes in vitro. Also blocks proliferation of rodent neonatal cardiomyocytes seen at low ANP concentrations in vitro. Tocris Bioscience 5498
      High affinity, selective ANP clearance receptor (NPR3) antagonist (Ki = 0.45 nM). Exhibits >20,000-fold selectivity for NPR3 over NPR1. Inhibits ANP-stimulated Na+/K+ pump activity in rabbit ventricular cardiomyocytes in vitro. Also blocks proliferation of rodent neonatal cardiomyocytes seen at low ANP concentrations in vitro. Tocris Bioscience 5498
      High affinity, selective NPR3 antagonist Tocris Bioscience 5498
      Natriuretic Peptide Receptor Tocris Bioscience 5498

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.635
Molar Refractivity: 245.1±0.5 cm3
#H bond acceptors: 20
#H bond donors: 15
#Freely Rotating Bonds: 27
#Rule of 5 Violations: 3
ACD/LogP: 3.58
ACD/LogD (pH 5.5): -1.78
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -1.82
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 341 Å2
Polarizability: 97.2±0.5 10-24cm3
Surface Tension: 55.6±7.0 dyne/cm
Molar Volume: 684.1±7.0 cm3

Click to predict properties on the Chemicalize site


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