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Search term: WKRWUYKLUMMAKG-WYGBAUISSA-L (Found by InChIKey (full match))
ChemSpider 2D Image | Ionomycin | C41H70CaO9

Ionomycin

  • Molecular FormulaC41H70CaO9
  • Average mass747.067 Da
  • Monoisotopic mass746.464600 Da
  • ChemSpider ID4949834

  • Charge - Charge

    Double-bond stereo - Double-bond stereo

    defined stereocentres - 14 of 14 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-Dihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyéthyl]-2,5'-diméthyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptaméthyl-9-oxo-11-oxydo-10,16-doc osadiénoate de calcium [French] [ACD/IUPAC Name]
10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, calcium salt, (4R,6S,8S,10Z ,12R,14R,16E,18R,19R,20S,21S)- (1:1) [ACD/Index Name]
200-664-3 [EINECS]
56092-82-1 [RN]
Calcium (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxo-1 0,16-docosadienoate [ACD/IUPAC Name]
Calcium-(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-19,21-dihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-11-oxido-9-oxo-1 0,16-docosadienoat [German] [ACD/IUPAC Name]
Ionomycin [Wiki]
Ionomycin (calcium salt)
Ionomycin calcium salt
MFCD00083634
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1416163 [DBID]
  • Experimental Physico-chemical Properties

    • Experimental Solubility:

      Soluble in ethanol (100 mM) and DMSO (25 mM) Hello Bio HB1001
      Soluble to 100 mM in ethanol and to 25 mM in DMSO Tocris Bioscience 1704
      Soluble to 100 mM in ethanol and to 25 mM in DMSO with gentle warming Tocris Bioscience 1704
  • Miscellaneous

    • Bio Activity:

      <p>Ionomycin calcium salt is a potent calcium ionophore which shows selectivity for Ca<sup>2+</sup> over Mg<sup>2+</sup> and K<sup>+</sup>. It acts as a Ca<sup>2+</sup> carrier and is the calcium salt of <a href="/ionomycin-free-acid.html" title="Ionomycin| Stimulates cytokine production | Hello Bio" target="_self">ionomycin</a>.</p> <p><br />Ionomycin directly stimulates store-regulated cation entry across biological membranes to enhance Ca<sup>2+</sup> influx and increase intracellular Ca<sup>2+</sup> concentration.</p> <p></p> <p><br />Ionomycin also synergies with <a href="/phorbol-12myristate-13acetate.html" title="PMA | Hello Bio" target="_self">phorbol myristate acetate</a> (PMA) to enhance activation of PKC and is frequently used in combination with PMA to stimulate T-cell activation and intracellular production of cytokines.</p> <p>Ionomycin also induces apoptosis.</p> <p><br /><a href="/a23187-free-acid.html" title="Calcium ionophore A23187 | Hello Bio" target="_self">Calcium ionophore A23187</a> also available.</p> Hello Bio HB1001
      <p>Ionomycin calcium salt is a potent calcium ionophore which shows selectivity for Ca<sup>2+</sup> over Mg<sup>2+</sup> and K<sup>+</sup>. It acts as a Ca<sup>2+</sup> carrier and is the calcium salt of <a href=/ionomycin-free-acid.html title=Ionomycin| Stimulates cytokine production | Hello Bio target=_self>ionomycin</a>.</p> <p><br />Ionomycin directly stimulates store-regulated cation entry across biological membranes to enhance Ca<sup>2+</sup> influx and increase intracellular Ca<sup>2+</sup> concentration.</p> <p></p> <p><br />Ionomycin also synergies with <a href=/phorbol-12myristate-13acetate.html title=PMA | Hello Bio target=_self>phorbol myristate acetate</a> (PMA) to enhance activation of PKC and is frequently used in combination with PMA to stimulate T-cell activation and intracellular production of cytokines.</p> <p>Ionomycin also induces apoptosis.</p> <p><br /><a href=/a23187-free-acid.html title=Calcium ionophore A23187 | Hello Bio target=_self>Calcium ionophore A23187</a> also available.</p> Hello Bio HB1001
      Calcium ionophore Tocris Bioscience 1704
      Calcium ionophore. Stimulates cytokine production. Hello Bio HB1001
      Calcium ionophore; more specific than A23187 (Cat. No. 1234). Tocris Bioscience 1704
      Calcium ionophore; more specific than A23187. Free Acid also available. Tocris Bioscience 1704
      Calcium Signaling Tocris Bioscience 1704
      Cell Biology Tocris Bioscience 1704
      Cell signaling/Ca<sup>2+</sup> signaling/General compounds Hello Bio HB1001
      General Calcium Signaling Agents Tocris Bioscience 1704
      Imaging, dyes, stains & labels/Ion indicators, ionophores & chelators Hello Bio HB1001
      Ion channels/Other/Ionophores Hello Bio HB1001
      Signal Transduction Tocris Bioscience 1704
      Type/Biochemicals & small molecules Hello Bio HB1001

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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