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- A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pK
a and binding affinity and evidence for intermolecular C–F⋯CN interactions. Jacob Olsen, Paul Seiler, Björn Wagner, Holger Fischer, Thomas Tschopp, Ulrike Obst-Sander, David W. Banner, Manfred Kansy, Klaus Müller, François Diederich
, Org. Biomol. Chem.
, 2004
, 2
, 1339