Results
1 -
10 of
75
(Click
here to explore results)
-
Catalytic, enantioselective synthesis of stilbenecis-diamines: A concise preparation of (−)-Nutlin-3, a potent p53/MDM2 inhibitor. Tyler A. Davis, Jeffrey N. Johnston
, Chem. Sci.
, 2011
, 2
, 1076
- Asymmetric organocatalysis: an enabling technology for medicinal chemistry. Bo Han, Xiang-Hong He, Yan-Qing Liu, Gu He, Cheng Peng, Jun-Long Li
, Chem. Soc. Rev.
, 2021
, 50
, 1522
- Dual-channel surface plasmon resonance monitoring of intracellular levels of the p53-MDM2 complex and caspase-3 induced by MDM2 antagonist Nutlin-3. Ling Wu, Yuqing Hu, Yuhan He, Yonghong Xia, Hanwen Lu, Zhong Cao, Xinyao Yi, Jianxiu Wang
, Analyst
, 2019
, 144
, 3959
- Solid-state nanopore analysis on conformation change of p53TAD–MDM2 fusion protein induced by protein–protein interaction. Hongsik Chae, Dong-Kyu Kwak, Mi-Kyung Lee, Seung-Wook Chi, Ki-Bum Kim
, Nanoscale
, 2018
, 10
, 17227
- Effective co-delivery of nutlin-3a and p53 genes via core–shell microparticles for disruption of MDM2–p53 interaction and reactivation of p53 in hepatocellular carcinoma. Pooya Davoodi, Madapusi P. Srinivasan, Chi-Hwa Wang
, J. Mater. Chem. B
, 2017
, 5
, 5816
- Energetics of a protein disorder–order transition in small molecule recognition. Cesar Mendoza-Martinez, Michail Papadourakis, Salomé Llabrés, Arun A. Gupta, Paul N. Barlow, Julien Michel
, Chem. Sci.
, 2022
, 13
, 5220
- Rapid identification of dual p53-MDM2/MDMX interaction inhibitors through virtual screening and hit-based substructure search. Si Chen, Xiang Li, Weirong Yuan, Yan Zou, Zhongwu Guo, Yifeng Chai, Wuyuan Lu
, RSC Adv.
, 2017
, 7
, 9989
- Recent applications of covalent chemistries in protein–protein interaction inhibitors. Alexandria M. Chan, Christopher C. Goodis, Elie G. Pommier, Steven Fletcher
, RSC Med. Chem.
, 2022
, 13
, 921
- Environment-sensitive turn-on fluorescent probes for p53–MDM2 protein–protein interaction. Tingting Liu, Yan Jiang, Zhenzhen Liu, Jin Li, Kun Fang, Chunlin Zhuang, Lupei Du, Hao Fang, Chunquan Sheng, Minyong Li
, Med. Chem. Commun.
, 2017
, 8
, 1668
- Single-molecule analysis of interaction between p53TAD and MDM2 using aerolysin nanopores. Sohee Oh, Mi-Kyung Lee, Seung-Wook Chi
, Chem. Sci.
, 2021
, 12
, 5883