Discovery of an NAD+ analogue with enhanced specificity for PARP1. Xiao-Nan Zhang, Albert T. Lam, Qinqin Cheng, Valentine V. Courouble, Timothy S. Strutzenberg, Jiawei Li, Yiling Wang, Hua Pei, Bangyan L. Stiles, Stan G. Louie, Patrick R. Griffin, Yong Zhang
, Chem. Sci.
, 2022
, 13
, 1982
Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors. Richard J. R. Elliott, Ashley Jarvis, Mohan B. Rajasekaran, Malini Menon, Leandra Bowers, Ray Boffey, Melanie Bayford, Stuart Firth-Clark, Rebekah Key, Rehan Aqil, Stewart B. Kirton, Dan Niculescu-Duvaz, Laura Fish, Filipa Lopes, Robert McLeary, Ines Trindade, Elisenda Vendrell, Felix Munkonge, Rod Porter, Trevor Perrior, Caroline Springer, Antony W. Oliver, Laurence H. Pearl, Alan Ashworth, Christopher J. Lord
, Med. Chem. Commun.
, 2015
, 6
, 1687