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- Systematic characterization of metabolic profiles of ingenol in rats by UPLC-Q/TOF-MS and NMR in combination with microbial biotransformation. Si-Jia Xiao, Shan-Shan Li, Bin Xie, Wei Chen, Xi-Ke Xu, Xian-Peng Zu, Yun-Heng Shen
, RSC Adv.
, 2021
, 11
, 37752
- 20-O-IngenolEZ, a catalytic topoisomerase II inhibitor, specifically inhibits cell proliferation and induces double-strand DNA breaks in BLM
-/-cells. Manami Watanabe, Yuta Kamada, Khosuke Miyazaki, Shoko Mizoguchi, Keiichi Matsuzaki, Susumu Kitanaka, Shohei Miyata
, Med. Chem. Commun.
, 2011
, 2
, 824
- Approaches to the synthesis of ingenol. Sanghee Kim, Jeffrey D. Winkler
, Chem. Soc. Rev.
, 1997
, 26
, 387
- Pharmaceuticals that contain polycyclic hydrocarbon scaffolds. Tegan P. Stockdale, Craig M. Williams
, Chem. Soc. Rev.
, 2015
, 44
, 7737
- Finding activity through rigidity: syntheses of natural products containing tricyclic bridgehead carbon centers. Zhi Xu, Xin Li, John A. Rose, Seth B. Herzon
, Nat. Prod. Rep.
, 2023
, 40
, 1393
- Balancing skeleton and functional groups in total syntheses of complex natural products: a case study of tigliane, daphnane and ingenane diterpenoids. Zhi Liu, Zhengwei Ding†, Kai Chen, Ming Xu, Tao Yu, Guanghu Tong, Hailong Zhang, Pengfei Li
, Nat. Prod. Rep.
, 2021
, 38
, 1589
- Total synthesis of natural derivatives and artificial analogs of 13-oxyingenol and their biological evaluation. Takayuki Ohyoshi, Yuki Tamura, Ichiro Hayakawa, Go Hirai, Yamato Miyazawa, Shota Funakubo, Mikiko Sodeoka, Hideo Kigoshi
, Org. Biomol. Chem.
, 2016
, 14
, 11426
- Recent advances in the total synthesis of pharmaceutically relevant diterpenes. Torsten Busch, Andreas Kirschning
, Nat. Prod. Rep.
, 2008
, 25
, 318
- Natural product synthesis in the age of scalability. Christian A. Kuttruff, Martin D. Eastgate, Phil S. Baran
, Nat. Prod. Rep.
, 2014
, 31
, 419
- In search of therapeutic candidates for HIV/AIDS: rational approaches, design strategies, structure–activity relationship and mechanistic insights. Dinesh Kumar, Pooja Sharma, Shabu, Ramandeep Kaur, Maloba M. M. Lobe, Girish K. Gupta, Fidele Ntie-Kang
, RSC Adv.
, 2021
, 11
, 17936