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Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 5 New Activities of CELMoDs, Cereblon E3 Ligase-modulating Drugs . Mary E. Matyskiela, Thomas Clayton, Joel W. Thompson, Christopher Carroll, Leslie Bateman, Laurie LeBrun, Philip P. Chamberlain
, 2020
, Pages 94-114
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 8 PROTAC Targeting BTK for the Treatment of Ibrutinib-resistant B-cell Malignancies . Yonghui Sun, Yu Rao
, 2020
, Pages 147-166
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 2 Structural and Biophysical Principles of Degrader Ternary Complexes . David Zollman, Alessio Ciulli
, 2020
, Pages 14-54
The Discovery and Utility of Chemical Probes in Target Discovery, CHAPTER 7 Targeted Protein Degradation Chemical Probes . C. Galdeano, X. Barril
, 2021
, Pages 150-181
Inhibitors of Protein–Protein Interactions: Small Molecules, Peptides and Macrocycles, Chapter 3 The Challenge of Prosecuting Intracellular Protein–Protein Interactions: A Multi-modality Examination of Chemical Matter Identification, Biophysical Characterization, and Membrane Permeability . L. Fan, W. T. McElroy, T. K. Sawyer, P. R. Sheth, D. M. Tellers
, 2021
, Pages 66-110
High Throughput Screening Methods: Evolution and Refinement, Chapter 12 Small-molecule-mediated Targeted Protein Degradation for Drug Discovery . Rohan E. J. Beckwith
, 2017
, Pages 252-274
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 6 Structure-based PROTAC Design . Darryl B. McConnell
, 2020
, Pages 115-134
Orphan Drugs and Rare Diseases, Chapter 15 The Discovery and Development of Ruxolitinib for the Treatment of Myelofibrosis . Kris Vaddi
, 2014
, Pages 419-439
Drug Repurposing, Chapter 5 Collaboration Models for Repurposing . Bruce Bloom
, 2022
, Pages 74-100
Protein Degradation with New Chemical Modalities: Successful Strategies in Drug Discovery and Chemical Biology, Chapter 3 Immediate and Selective Control of Protein Abundance Using the dTAG System . Behnam Nabet, Nathanael S. Gray
, 2020
, Pages 55-74