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Chemistries of bifunctional PROTAC degraders . Chaoguo Cao, Ming He, Liguo Wang, Yuna He, Yu Rao
, Chem. Soc. Rev.
, 2022
, 51
, 7066
E3 ligase ligand chemistries: from building blocks to protein degraders . Izidor Sosič, Aleša Bricelj, Christian Steinebach
, Chem. Soc. Rev.
, 2022
, 51
, 3487
Innovative, combinatorial and high-throughput approaches to degrader synthesis . Rebecca Stevens, James D. F. Thompson, Julie C. L. Fournier, Glenn A. Burley, David J. Battersby, Afjal H. Miah
, Chem. Soc. Rev.
, 2024
Methods to characterize and discover molecular degraders in cells . Zhi Lin, Christina M. Woo
, Chem. Soc. Rev.
, 2022
, 51
, 7115
PROTACs: past, present and future . Ke Li, Craig M. Crews
, Chem. Soc. Rev.
, 2022
, 51
, 5214
Research progress of anticancer drugs targeting CDK12 . Zhijia Yan, Yongli Du, Haibin Zhang, Yong Zheng, Huiting Lv, Ning Dong, Fang He
, RSC Med. Chem.
, 2023
, 14
, 1629
Development of hypoxia-activated PROTAC exerting a more potent effect in tumor hypoxia than in normoxia . Weiyan Cheng, Shasha Li, Xueqian Wen, Siyuan Han, Suhua Wang, Han Wei, Zhizhen Song, Yueqin Wang, Xin Tian, Xiaojian Zhang
, Chem. Commun.
, 2021
, 57
, 12852
Developing degraders: principles and perspectives on design and chemical space . Hannah J. Maple, Nat Clayden, Anne Baron, Callum Stacey, Robert Felix
, Med. Chem. Commun.
, 2019
, 10
, 1755
Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development . Mark S. Cooper, Mark C. Norley, Simon Armitage, Joel O. Cresser-Brown, Anthony K. Edmonds, Sean Goggins, Jonathan P. Hopewell, Burhan Karadogan, Kevin A. Knights, Toby J. Nash, Catherine S. Oakes, William J. O'Neill, Simon J. Pridmore, Hannah J. Maple, Graham P. Marsh
, Org. Biomol. Chem.
, 2023
, 21
, 8344
Development of a covalent cereblon-based PROTAC employing a fluorosulfate warhead . Radosław P. Nowak, Leah Ragosta, Fidel Huerta, Hu Liu, Scott B. Ficarro, Justin T. Cruite, Rebecca J. Metivier, Katherine A. Donovan, Jarrod A. Marto, Eric S. Fischer, Breanna L. Zerfas, Lyn H. Jones
, RSC Chem. Biol.
, 2023
, 4
, 906