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- Discovery of novel amino-pyrimidine inhibitors of the insulin-like growth factor 1 (IGF1R) and insulin receptor (INSR) kinases; parallel optimization of cell potency and hERG inhibition. Heather Tye, Ulrich Guertler, Marco H. Hofmann, Moriz Mayer, Sandeep Pal, Georg Rast, Michael P. Sanderson, Otmar Schaaf, Matthias Treu, Stephan K. Zahn
, Med. Chem. Commun.
, 2015
, 6
, 1244
- Small molecule inhibitors in pancreatic cancer. Jufeng Sun, Cecilia C. Russell, Christopher J. Scarlett, Adam McCluskey
, RSC Med. Chem.
, 2020
, 11
, 164