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A novel LC-MS/MS method for simultaneous estimation of acalabrutinib and its active metabolite acalabrutinib M27 in human plasma and application to a human pharmacokinetic study . Venkat Rao Valluri, Naresh Kumar Katari, Chirag Khatri, Pankaj Kasar, Srinivasa Rao Polagani, Sreekanth Babu Jonnalagadda
, RSC Adv.
, 2022
, 12
, 6631
Advances in covalent kinase inhibitors . Ayah Abdeldayem, Yasir S. Raouf, Stefan N. Constantinescu, Richard Moriggl, Patrick T. Gunning
, Chem. Soc. Rev.
, 2020
, 49
, 2617
4-Aminopyrazolopyrimidine scaffold and its deformation in the design of tyrosine and serine/threonine kinase inhibitors in medicinal chemistry . Xiaolu Chen, Yajiao Huang, Wanghan Xu, Yuepiao Cai, Yuanrong Yang
, RSC Med. Chem.
, 2022
, 13
, 1008
Palladium catalyzed C–C and C–N bond forming reactions: an update on the synthesis of pharmaceuticals from 2015–2020 . Jayachandra Rayadurgam, Sravani Sana, M. Sasikumar, Qiong Gu
, Org. Chem. Front.
, 2021
, 8
, 384
Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine . Sijun Pan, Aixiang Ding, Yisi Li, Yaxin Sun, Yueqin Zhan, Zhenkun Ye, Ning Song, Bo Peng, Lin Li, Wei Huang, Huilin Shao
, Chem. Soc. Rev.
, 2023
, 52
, 5706
Formation of pharmaceutical salts and cocrystals via vapour-assisted tumbling (VAT) – a solvent efficient process . Alexander J. Stirk, Fabio E. S. Souza, Jenny Gerster, Fatemeh M. Mir, Avedis Karadeolian, Allan W. Rey
, Green Chem.
, 2022
, 24
, 1505
Design, synthesis and biological evaluation of novel 2-phenyl pyrimidine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors . Xinyu Li, Binyu Shi, Yu Teng, Yu Cheng, Huizhu Yang, Jiurong Li, Lianjian Wang, Siying He, Qidong You, Hua Xiang
, Med. Chem. Commun.
, 2019
, 10
, 294
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors . João D. Seixas, Bárbara B. Sousa, Marta C. Marques, Ana Guerreiro, Rui Traquete, Tiago Rodrigues, Inês S. Albuquerque, Marcos F. Q. Sousa, Ana R. Lemos, Pedro M. F. Sousa, Tiago M. Bandeiras, Di Wu, Shelby K. Doyle, Carol V. Robinson, Angela N. Koehler, Francisco Corzana, Pedro M. Matias, Gonçalo J. L. Bernardes
, RSC Chem. Biol.
, 2020
, 1
, 251
Mechanism of covalent binding of ibrutinib to Bruton's tyrosine kinase revealed by QM/MM calculations . Angus T. Voice, Gary Tresadern, Rebecca M. Twidale, Herman van Vlijmen, Adrian J. Mulholland
, Chem. Sci.
, 2021
, 12
, 5511
Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d ]pyrimidine scaffold . Daniel J. Baillache, Asier Unciti-Broceta
, RSC Med. Chem.
, 2020
, 11
, 1112